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Glass-Crystal Growth Mode for Testosterone Propionate
被引:64
作者:
Shtukenberg, Alexander
[1
]
Freundenthal, John
[1
]
Gunn, Erica
[2
]
Yu, Lian
[2
]
Kahr, Bart
[1
]
机构:
[1] NYU, Dept Chem, New York, NY 10003 USA
[2] Univ Wisconsin, Sch Pharm, Madison, WI 53705 USA
基金:
美国国家科学基金会;
关键词:
NUCLEATION-BASED CRYSTALLIZATION;
O-TERPHENYL;
TRANSITION;
MECHANISM;
LIQUID;
D O I:
10.1021/cg200640g
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
The recently discovered glass-crystal (GC) growth mode in some glass-forming liquids is characterized by strong and abrupt growth rate enhancement just in the vicinity of the glass transition temperature. GC growth previously has been observed in only 10 compounds. The data on testosterone propionate presented here indicate the fastest GC growth acceleration observed to date. Moreover, testosterone propionate is the first compound to show a helically twisted morphology concomitant with GC growth. It has been previously stated that an aryl ring is a prerequisite of GC growth, but testosterone propionate obviates that claim.
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页码:4458 / 4462
页数:5
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