Cardiotoxicity of radiation therapy in esophageal cancer

被引:23
作者
Vosmik, Milan [1 ]
Hodek, Miroslav [1 ]
Buka, David [1 ]
Sykorova, Petra [1 ]
Grepl, Jakub [1 ]
Paluska, Petr [1 ]
Paulikova, Simona [1 ]
Sirak, Igor [1 ]
机构
[1] Univ Hosp Hradec Kralove, Dept Oncol & Radiotherapy, Hradec Kralove, Czech Republic
关键词
Esophageal cancer; Radiation therapy; Cardiac toxicity; SQUAMOUS-CELL CARCINOMA; CLINICAL TARGET VOLUME; MODULATED ARC THERAPY; PROTON-BEAM THERAPY; DEFINITIVE CHEMORADIOTHERAPY; PERICARDIAL-EFFUSION; CARDIAC TOXICITY; HEART-DISEASE; PREOPERATIVE CHEMORADIOTHERAPY; TIME TRENDS;
D O I
10.1016/j.rpor.2020.02.005
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
With a development of radiotherapeutic techniques, availability of radiotherapy data on cardiotoxicity, and slowly improving esophageal cancer outcomes, an increasing emphasis is placed on the heart protection in radiation treated esophageal cancer patients. Radiation induced heart complications encompass mainly pericardial disease, cardiomyopathy, coronary artery atherosclerosis, valvular heart disease, and arrhythmias. The most frequent toxicity is pericardial effusion which is usually asymptomatic in the majority of patients. The use of modern radiotherapy techniques is expected to reduce the risk of cardiotoxicity, although this expectation has to be confirmed by clinical data. (C) 2020 Greater Poland Cancer Centre. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:318 / 322
页数:5
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