Vagus nerve stimulation

被引：19

作者：

Amar, Arun Paul ^{[1
]}

Levy, Michael L. ^{[2
,3
]}

Liu, Charles Y. ^{[4
]}

Apuzzo, Michael L. J.

机构：

[1] Univ Calif San Francisco, San Francisco, CA 94143 USA

[2] Childrens Hosp, Div Neurosurg, San Diego, CA 92123 USA

[3] Univ Calif San Diego, Sch Med, San Diego, CA 92123 USA

[4] Univ So Calif, Keck Sch Med, Dept Neurol Surg, Los Angeles, CA 90033 USA

来源：

PROCEEDINGS OF THE IEEE | 2008年 / 96卷 / 07期

关键词：

depression; epilepsy; neurostimulation; seizure; vagus nerve stimulation;

D O I：

10.1109/JPROC.2008.922569

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Vagus nerve stimulation (VNS) is a safe and reliable treatment adjunct for patients with medically intractable epilepsy. it is both a preventive and an abortive form of therapy, potentially effective against both partial and generalized seizures in adults and children. VNS also has a number of serendipitous effects on mood, memory, and attention and has been approved for the treatment of refractory depression. Because of its pleiotropic effects, it holds promise for several other diseases as well. its principal limitations are its unknown mechanism of action, the low likelihood of complete cure, and the inability to predict which patients will derive substantial benefit. This paper reviews the theoretical rationale, practical background, and clinical applications of VNS therapy.

引用

页码：1142 / 1151

页数：10

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