DABCO: an efficient promoter for the acetylation of carbohydrates and other substances under solvent-free conditions

被引：15

作者：

Ch, Ratnasekhar ^{[1
]}

Tyagi, Mohit ^{[1
]}

Patil, Premanand Ramrao ^{[1
]}

Kartha, K. P. Ravindranathan ^{[1
]}

机构：

[1] Natl Inst Pharmaceut Educ & Res, Dept Med Chem, Sas Nagar 160062, Punjab, India

来源：

TETRAHEDRON LETTERS | 2011年 / 52卷 / 44期

关键词：

DABCO; Acetylation; Carbohydrates; Alcohols; PER-O-ACETYLATION; PRIMARY HYDROXYL PROTECTION; CATALYZED ACETYLATION; SUGAR ACETATES; ALCOHOLS; ACYLATION; THIOGLYCOSIDES; POWERFUL; 4-DIALKYLAMINOPYRIDINES; PERACETYLATION;

D O I：

10.1016/j.tetlet.2011.08.141

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple, mild and efficient solvent-free method for the acetylation of carbohydrates, and their partially protected derivatives, as well as non-carbohydrate substances in excellent yields in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) is described with the advantage of tolerance to various functional groups, short reaction time and ease of product isolation. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：5841 / 5846

页数：6

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