Distribution of Antiseptic Resistance Genes qacA, qacB, and smr in Methicillin-Resistant Staphylococcus aureus Isolated in Toronto, Canada, from 2005 to 2009

被引：73
作者：
Longtin, Jean [1 ,2 ]
Seah, Christine [2 ]
Siebert, Krystal [2 ]
McGeer, Allison [3 ]
Simor, Andrew [4 ]
Longtin, Yves [1 ]
Low, Donald E. [2 ,3 ]
Melano, Roberto G. [2 ,3 ]
机构：
[1] Univ Laval, Infect Dis Res Ctr, Quebec City, PQ G1V 4G2, Canada
[2] Ontario Agcy Hlth Protect & Promot, Publ Hlth Labs, Toronto, ON, Canada
[3] Mt Sinai Hosp, Dept Microbiol, Toronto, ON M5G 1X5, Canada
[4] Sunnybrook Hlth Sci Ctr, Dept Microbiol, Toronto, ON M4N 3M5, Canada
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2011年 / 55卷 / 06期
关键词：
CHLORHEXIDINE GLUCONATE; SUSCEPTIBILITIES; INFECTION; EPIDEMIOLOGY; SURGERY;
D O I：
10.1128/AAC.01707-10
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Decreased susceptibility to chlorhexidine gluconate (CHDN) in methicillin-resistant Staphylococcus aureus (MRSA) is associated with the qacA, qacB, and smr genes, encoding efflux pumps. A total of 334 MRSA isolates were collected from two Canadian intensive care units between 2005 and 2009. We identified the qacAB genes in 7 strains (2%; 2 qacA genes and 5 qacB genes) and the smr gene in 23 (7%) strains. CHDN minimal bactericidal concentrations were slightly higher for strains harboring smr genes.
引用
收藏
页码：2999 / 3001
页数：3
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