The Role of Fungi in Atopic Dermatitis

被引：24

作者：

Glatz, Martin ^{[1
,2
]}

Bosshard, Philipp ^{[3
]}

Schmid-Grendelmeier, Peter ^{[1
,2
]}

机构：

[1] Univ Zurich Hosp, Dept Dermatol, Allergy Unit, Gloriastr 31, CH-8091 Zurich, Switzerland

[2] Christine Kuhne Ctr Allergy Res & Educ, Herman Burchard Str 1, CH-7265 Davos, Switzerland

[3] Univ Zurich Hosp, Dept Dermatol, Mycol Lab, Gloriastr 31, CH-8091 Zurich, Switzerland

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2017年 / 37卷 / 01期

关键词：

Atopic dermatitis; Malassezia spp; Sensitization; MANGANESE SUPEROXIDE-DISMUTASE; YEAST MALASSEZIA-SYMPODIALIS; SEQUENCE SIMILARITIES; SYSTEMIC KETOCONAZOLE; GENUS MALASSEZIA; FURFUR ALLERGENS; HUMAN SKIN; SERUM IGE; DUST-MITE; T-CELLS;

D O I：

10.1016/j.iac.2016.08.012

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

There is little doubt that Malassezia spp plays a role in atopic dermatitis because it may interact with the local skin immune responses and barrier function, and sensitization against this skin-colonizing yeast can correlate with disease activity. Also, antifungal therapy shows beneficial effects in some patients. However, the pathogenetic mechanism and mutual interaction between Malassezia spp and atopic dermatitis still remain partly unclear and need further investigation.

引用

页码：63 / +

页数：13

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