Identification and Characterization of Novel NADPH Oxidase Inhibitors for Suppression of Influenza a virus-induced Lung Inflammation

被引:0
|
作者
Sun, Aiming [1 ]
De la Cruz, Juan [2 ]
Ganesh, Thota [1 ]
Taylor, Andrew [2 ]
Diebold, Becky [3 ]
Smith, Susan M. E. [3 ]
Zhu, Yerun [3 ]
McCoy, James [3 ]
Gangappa, Shivaprakash [2 ]
Lambeth, J. Dave [3 ]
机构
[1] Emory Univ, Emory Inst Drug Discovery, Atlanta, GA 30322 USA
[2] Emory Univ, Ctr Dis Control & Prevent, Influenza Div, Atlanta, GA 30322 USA
[3] Emory Univ, Dept Pathol, Atlanta, GA 30322 USA
关键词
D O I
10.1016/j.freeradbiomed.2011.10.383
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:S108 / S108
页数:1
相关论文
共 50 条
  • [1] Impact of NADPH Oxidase Inhibition on Influenza A Virus-induced Inflammation
    Patel, Jenish R.
    Christoph, Bradley T.
    Hussain, Sakina F.
    Vora, Keyur P.
    Ranjan, Priya
    Sambhara, Suryaprakash
    Gangappa, Shivaprakash
    JOURNAL OF IMMUNOLOGY, 2009, 182
  • [2] NOX1 OXIDASE PROTECTS AGAINST INFLUENZA A VIRUS-INDUCED LUNG INFLAMMATION
    Selemidis, S.
    Seow, H. J.
    Broughton, B.
    Bozinovski, S.
    Vinh, A.
    Stambas, J.
    Sobey, C. G.
    Drummond, G. R.
    Vlahos, R.
    RESPIROLOGY, 2012, 17 : 33 - 33
  • [3] Nox1 Oxidase Suppresses Influenza A Virus-Induced Lung Inflammation and Oxidative Stress
    Selemidis, Stavros
    Seow, Huei Jiunn
    Broughton, Brad R. S.
    Vinh, Antony
    Bozinovski, Steven
    Sobey, Christopher G.
    Drummond, Grant R.
    Vlahos, Ross
    PLOS ONE, 2013, 8 (04):
  • [4] INHIBITION OF NOX1 OXIDASE EXACERBATES INFLUENZA A VIRUS-INDUCED LUNG INFLAMMATION.
    Selemidis, Stavros
    Seow, Huei Juinn
    Broughton, Brad
    Bozinovski, Steven
    Vinh, Antony
    Stambas, John
    Sobey, Christopher
    Drummond, Grant
    Vlahos, Ross
    FASEB JOURNAL, 2012, 26
  • [5] Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation
    Vlahos, Ross
    Stambas, John
    Bozinovski, Steven
    Broughton, Brad R. S.
    Drummond, Grant R.
    Selemidis, Stavros
    PLOS PATHOGENS, 2011, 7 (02)
  • [6] Novel endosomal NOX2 oxidase inhibitor ameliorates pandemic influenza A virus-induced lung inflammation in mice
    To, Eunice E.
    Luong, Raymond
    Diao, Jiayin
    O' Leary, John J.
    Brooks, Doug A.
    Vlahos, Ross
    Selemidis, Stavros
    RESPIROLOGY, 2019, 24 (10) : 1011 - 1017
  • [7] Role of reactive persulfide species in influenza virus-induced lung inflammation
    Ichikawa, Tomohiro
    Takita, Katsuya
    Ito, Tatsunori
    Kyogoku, Yorihiko
    Numakura, Tadahisa
    Yamada, Mitsuhiro
    Akaike, Takaaki
    Ichinose, Masakazu
    Sugiura, Hisatoshi
    RESPIROLOGY, 2021, 26 : 9 - 10
  • [8] Soloxolone methyl inhibits influenza virus replication and reduces virus-induced lung inflammation
    Andrey V. Markov
    Alexandra V. Sen’kova
    Dawid Warszycki
    Oksana V. Salomatina
    Nariman F. Salakhutdinov
    Marina A. Zenkova
    Evgeniya B. Logashenko
    Scientific Reports, 7
  • [9] Soloxolone methyl inhibits influenza virus replication and reduces virus-induced lung inflammation
    Markov, Andrey V.
    Sen'kova, Alexandra V.
    Warszycki, Dawid
    Salomatina, Oksana V.
    Salakhutdinov, Nariman F.
    Zenkova, Marina A.
    Logashenko, Evgeniya B.
    SCIENTIFIC REPORTS, 2017, 7
  • [10] Role of reactive persulfide species in influenza virus-induced lung inflammation in mice
    Takita, Katsuya
    Sugiura, Hisatoshi
    Ichikawa, Tomohiro
    Tadahhisa, Numakura
    Taizou, Hirano
    Yamada, Mitsuhiro
    Akaike, Takaaki
    Masakazu, Ichinose
    EUROPEAN RESPIRATORY JOURNAL, 2020, 56