Direct Oral Anticoagulants and Women

被引：19

作者：

Cohen, Hannah ^{[1
,2
]}

Arachchillage, Deepa R. J. ^{[3
,4
]}

Beyer-Westendorf, Jan ^{[5
]}

Middeldorp, Saskia ^{[6
]}

Kadir, Rezan A. ^{[7
,8
]}

机构：

[1] UCL, Dept Haematol, Haemostasis Res Unit, London, England

[2] Univ Coll London Hosp NHS Fdn Trust, Dept Haematol, London, England

[3] Dept Haematol, Imperial Coll Healthcare NHS Trust, London, England

[4] Imperial Coll London, Dept Haematol, London, England

[5] Univ Hosp Carl Gustav Carus, Tech Univ Dresden, Ctr Vasc Med & Dept Med 3, Dresden, Germany

[6] Univ Amsterdam, Acad Med Ctr, Dept Vasc Med, Holland, MI USA

[7] Royal Free Hosp NHS Fdn Trust, Katharine Dormandy Haemophilia Ctr & Thrombosis U, London, England

[8] Royal Free Hosp NHS Fdn Trust, Dept Obstet & Gynaecol, London, England

来源：

SEMINARS IN THROMBOSIS AND HEMOSTASIS | 2016年 / 42卷 / 07期

关键词：

direct oral anticoagulants; fertility; pregnancy; lactation; abnormal uterine bleeding; heavy menstrual bleeding; SYMPTOMATIC VENOUS THROMBOEMBOLISM; RANDOMIZED CONTROLLED-TRIAL; QUALITY-OF-LIFE; PRESCRIBING PRACTICE; INTRAUTERINE SYSTEM; ORTHOPEDIC-SURGERY; BLEEDING DISORDERS; POSTPARTUM PERIOD; TRANEXAMIC ACID; RIVAROXABAN;

D O I：

10.1055/s-0036-1592304

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Direct oral anticoagulants (DOACs) provide an effective, safe, and convenient therapeutic alternative to warfarin and other vitamin K antagonists (VKAs), and are now established for a wide range of indications. The use of DOACs in women merits special consideration due to two main situations: first, in relation to fertility, pregnancy, and lactation in women of reproductive age; second, because of their bleeding risk, leading to abnormal uterine and/or other genital tract bleeding. This review focuses on these two clinical situations, including approaches to management in the context of available information.

引用

页码：789 / 797

页数：9

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