Axially chiral N-heterocyclic carbene gold(I) complex catalyzed asymmetric Friedel-Crafts/cyclization reaction of nitrogen-tethered 1,6-enynes with indole derivatives

被引：34

作者：

Yang, Jinming ^{[1
,2
]}

Zhang, Rui ^{[1
,2
]}

Wang, Wenfeng ^{[1
,2
]}

Zhang, Zhen ^{[1
,2
]}

Shi, Min ^{[1
,2
,3
]}

机构：

[1] E China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai 200237, Peoples R China

[2] E China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Shanghai 200237, Peoples R China

[3] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 2011年 / 22卷 / 23期

基金：

中国国家自然科学基金;

关键词：

ENANTIOSELECTIVE INTRAMOLECULAR HYDROAMINATION; ARYLBORONIC ACIDS; PALLADIUM COMPLEXES; METAL-COMPLEXES; NHC LIGANDS; CYCLOISOMERIZATION; CYCLIZATION; ENYNES; CHEMISTRY; PLATINUM;

D O I：

10.1016/j.tetasy.2011.12.004

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A class of axially chiral NHC-Au(I) complexes has been applied to the asymmetric Friedel-Crafts/cyclization reaction of nitrogen-tethered 1,6-enynes 14 with indole derivatives 15, affording the corresponding Friedel-Crafts and intramolecular cyclization products 16 in good yields and with moderate ee values under mild conditions. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：2029 / 2038

页数：10

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