Adapting Imaging Protocols for PET-CT and PET-MRI for Immunotherapy Monitoring

被引:10
作者
Beuthien-Baumann, Bettina [1 ]
Sachpekidis, Christos [2 ]
Gnirs, Regula [1 ]
Sedlaczek, Oliver [1 ,3 ]
机构
[1] Deutsch Krebsforschungszentrum Heidelberg, Radiol, Neuenheimer Feld 280, D-69120 Heidelberg, Germany
[2] Deutsch Krebsforschungszentrum, Klin Kooperat Seinheit Nukl Med, Neuenheimer Feld 280, D-69120 Heidelberg, Germany
[3] Univ Klinikum Heidelberg, Klin Diagnost & Intervent Radiol, Neuenheimer Feld 420, D-69120 Heidelberg, Germany
关键词
PET-CT; PET-MRI; immunotherapy; F-18-FDG PET/CT; GUIDELINES; CRITERIA; PET/MRI; BENEFIT; LESIONS;
D O I
10.3390/cancers13236019
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Simple Summary In this review, we discuss the possible advantages and methods to overcome potential obstacles of applying combined imaging protocols of PET-CT and PET-MRI, within the context of staging and restaging of patients under immunotherapy, in order to achieve "multi-hybrid imaging" in one single visit. Hybrid imaging with positron emission tomography (PET) in combination with computer tomography (CT) is a well-established diagnostic tool in oncological staging and restaging. The combination of PET with magnetic resonance imaging (MRI) as a clinical scanner was introduced approximately 10 years ago. Although MRI provides superb soft tissue contrast and functional information without the radiation exposure of CT, PET-MRI is not as widely introduced in oncologic imaging as PET-CT. One reason for this hesitancy lies in the relatively long acquisition times for a PET-MRI scan, if the full diagnostic potential of MRI is exploited. In this review, we discuss the possible advantages of combined imaging protocols of PET-CT and PET-MRI, within the context of staging and restaging of patients under immunotherapy, in order to achieve "multi-hybrid imaging" in one single patient visit.
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页数:9
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