Method development and validation for the simultaneous determination of organic and inorganic acids by capillary zone electrophoresis

The separation of organic and inorganic acids was performed by capillary zone electrophoresis using indirect UV detection. Optimum conditions for the separation of 11 anions were investigated. This method was applied for the simultaneous determination of organic and inorganic anions in foods and beverage samples. The relative standard deviation (R.S.D.) for the analysis of anions was less than 1% for the migration time and 1-4% for the peak area (n=18). The detection limits was from 0.006 to 1.072 mg/l for the 11 anions. This newly developed method is rapid, sensitive and quantitative and can be readily applied to real food and beverage samples for quantitative analysis.