Haematological parameters of parvovirus B19 infection in 13 fetuses with hydrops foetalis

被引：31
作者：
Forestier, F
Tissot, JD
Vial, Y
Daffos, F
Hohlfeld, P [1 ]
机构：
[1] CHU Vaudois, Dept Gynecol & Obstet, CH-1011 Lausanne, Switzerland
[2] Inst Puericulture, Serv Med & Biol Foetales, F-75014 Paris, France
[3] Fdn Ctr Transfus CRS, Lausanne, Switzerland
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 1999年 / 104卷 / 04期
关键词：
fetal blood sampling; human parvovirus B19; hydrops foetalis; prenatal diagnosis; intrauterine transfusion;
D O I：
10.1046/j.1365-2141.1999.01241.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Thirteen cases of fetal parvovirus B19 infection with hydrops foetalis are reported, Viral DNA was identified by polymerase chain reaction (PCR) of amniotic fluid sampled between the 19th and the 29th week of gestation. Haematological examination revealed severe anaemia in all cases and thrombocytopenia in 11/13 cases, which was severe in two cases. Six fetuses died in utero: two after intrauterine transfusion, Complete recovery was observed in seven fetuses; five cases were treated by intrauterine transfusions, and in two cases spontaneous recovery occurred. Upon follow-up, no case of congenital anaemia was observed.
引用
收藏
页码：925 / 927
页数：3
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