Simultaneous electrochemical determination of dopamine and uric acid based on MoS2 nanoflowers-graphene/ITO electrode

被引：48

作者：

Guo, Xinrui ^{[1
]}

Yue, Hongyan ^{[1
]}

Song, Shanshan ^{[1
]}

Huang, Shuo ^{[2
]}

Gao, Xin ^{[1
]}

Chen, Hongtao ^{[1
]}

Wu, Pengfei ^{[1
]}

Zhang, Teng ^{[1
]}

Wang, Zengze ^{[1
]}

机构：

[1] Harbin Univ Sci & Technol, Sch Mat Sci & Engn, Harbin 150040, Peoples R China

[2] Harbin Med Univ, Dept Neurol, Affiliated Hosp 1, Harbin 150001, Peoples R China

来源：

MICROCHEMICAL JOURNAL | 2020年 / 154卷

关键词：

MoS2; nanoflowers; Graphene; Dopamine; Uric acid; Electrochemical biosensor; GLASSY-CARBON ELECTRODE; HYDROGEN EVOLUTION; GOLD NANOPARTICLES; ASCORBIC-ACID; SENSOR; NANOCOMPOSITE; NANOSHEET; COMPOSITE; OXIDE; BIOSENSOR;

D O I：

10.1016/j.microc.2019.104527

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

MoS2 nanoflowers (NFs) prepared by hydrothermal synthesis were mixed with graphene oxide (GO) suspension prepared by Hummers method. Then, the mixture was spray coated on indium tin oxide (ITO) glass. After heatment, MoS2 NFs-reduced GO/ITO (MoS2 NFs-rGO/ITO) was obtained and used as a working electrode to electrochemically detect dopamine and uric acid simultaneously. The results are as follows: MoS2 NFs with the diameter of similar to 1 mu m are composed by nanosheets and the graphene with a high transparence and large number of folds is coated on the surface of MoS2 NFs. A large number of holes form in the electrode so that bioactive molecules can easily enter and contact with the hybrid. The electrode exhibits a high sensitivity (2.29 and 1.88 mu A mu M-1) for the determination of dopamine and uric acid. The electrode also shows a low detection of limit, good anti-interference and stability. And it can be used for detecting real biomolecules.

引用

页数：7

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