Substrate effects on interactions of lipid bilayer assemblies with bound nanoparticles

被引：14

作者：

Goertz, Matthew P. ^{[1
]}

Goyal, Nikita ^{[1
]}

Bunker, Bruce C. ^{[1
]}

Montano, Gabriel A. ^{[1
]}

机构：

[1] Sandia & Los Alamos Natl Labs, Ctr Integrated Nanotechnol, Albuquerque, NM USA

来源：

JOURNAL OF COLLOID AND INTERFACE SCIENCE | 2011年 / 358卷 / 02期

关键词：

Nanoparticles; Self-assembly; Lipid bilayer; Biosensors; RESONANCE ENERGY-TRANSFER; MEMBRANES; CHOLESTEROL; LIPOSOMES; BEHAVIOR;

D O I：

10.1016/j.jcis.2011.02.063

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Understanding the interactions of nanoparticles with lipid membranes is crucial in establishing the mechanisms that govern assembly of membrane-based nanocomposites, nanotoxicology, and biomimetic inspired self-assembly. In this study, we explore binding of charged nanoparticles to lipid bilayers, both as liposomes and substrate supported assemblies. We find that the presence of a solid-support, regardless of curvature, eliminates the ability of zwitterionic fluid phase lipids to bind charged nanoparticles. (C) 2011 Elsevier Inc. All rights reserved.

引用

页码：635 / 638

页数：4

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