Imaging language pathways predicts postoperative naming deficits

被引：44

作者：

Powell, H. W. R. ^{[1
]}

Parker, G. J. M. ^{[2
]}

Alexander, D. C. ^{[3
]}

Symms, M. R. ^{[1
]}

Boulby, P. A. ^{[1
]}

Barker, G. J. ^{[4
]}

Thompson, P. J. ^{[1
]}

Koepp, M. J. ^{[1
]}

Duncan, John S. ^{[1
]}

机构：

[1] UCL, Inst Neurol, Dept Clin & Expt Epilepsy, London, England

[2] Univ Manchester, Manchester M13 9PL, Lancs, England

[3] UCL, Dept Comp Sci, London WC1E 6BT, England

[4] Kings Coll London, Inst Psychiat, Dept Clin Neurosci, London, England

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 2008年 / 79卷 / 03期

基金：

英国工程与自然科学研究理事会; 英国医学研究理事会; 英国惠康基金;

关键词：

D O I：

10.1136/jnnp.2007.126078

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Naming difficulties are a well recognised, but difficult to predict, complication of anterior temporal lobe resection (ATLR) for refractory epilepsy. We used MR tractography preoperatively to demonstrate the structural connectivity of language areas in patients undergoing dominant hemisphere ATLR. Greater lateralisation of tracts to the dominant hemisphere was associated with greater decline in naming function. We suggest that this method has the potential to predict language deficits in patients undergoing ATLR.

引用

页码：327 / 330

页数：4

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