In vivo tracking of tumor-specific T cells

被引:53
|
作者
Yee, C
Riddell, SR
Greenberg, PD
机构
[1] Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA
[2] Univ Washington, Med Ctr, Seattle, WA 98195 USA
关键词
D O I
10.1016/S0952-7915(00)00196-5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Novel immunologic assays now enable visualization of the antigen-specific response to an extent not previously possible. Assessment of not only the numeric frequency but also the functional properties of individual tumor-specific T cells in the endogenous and manipulated immune response has provided insights that will facilitate the development of immunotherapeutic strategies.
引用
收藏
页码:141 / 146
页数:6
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