In vivo tracking of tumor-specific T cells

被引:53
|
作者
Yee, C
Riddell, SR
Greenberg, PD
机构
[1] Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA
[2] Univ Washington, Med Ctr, Seattle, WA 98195 USA
关键词
D O I
10.1016/S0952-7915(00)00196-5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Novel immunologic assays now enable visualization of the antigen-specific response to an extent not previously possible. Assessment of not only the numeric frequency but also the functional properties of individual tumor-specific T cells in the endogenous and manipulated immune response has provided insights that will facilitate the development of immunotherapeutic strategies.
引用
收藏
页码:141 / 146
页数:6
相关论文
共 50 条
  • [1] Tracking down tumor-specific T cells
    Reading, James
    Foster, Kane
    Joshi, Kroopa
    Chain, Benny
    CANCER CELL, 2022, 40 (04) : 351 - 353
  • [2] Universal tumor-specific T cells: Redirecting T cells to tagged antigens in vivo
    Davila, Eduardo
    Geng, Degui
    Srivastava, Ratika
    Bansal, Navneeta
    Li, Chaoyang
    JOURNAL OF IMMUNOLOGY, 2012, 188
  • [3] Targeting tumor-specific T cells
    HOWES, L. A. U. R. A.
    CHEMICAL & ENGINEERING NEWS, 2020, 98 (41) : 7 - 7
  • [4] In vivo requirements for activation of tumor-specific CD4+T cells
    Corthay, A
    Bogen, B
    INTERNATIONAL JOURNAL OF CANCER, 2002, : 156 - 156
  • [5] Tumor-specific CD4+ T cells maintain effector and memory tumor-specific CD8+ T cells
    Church, Sarah E.
    Jensen, Shawn M.
    Antony, Paul A.
    Restifo, Nicholas P.
    Fox, Bernard A.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2014, 44 (01) : 69 - 79
  • [6] Tumor-specific regulatory T cells in cancer patients
    Piersma, Sytse J.
    Welters, Marij J. P.
    van der Burg, Sjoerd H.
    HUMAN IMMUNOLOGY, 2008, 69 (4-5) : 241 - 249
  • [7] Molecular Imaging in Tracking Tumor-Specific Cytotoxic T Lymphocytes (CTLs)
    Liu, Zhiyi
    Li, Zheng
    THERANOSTICS, 2014, 4 (10): : 990 - 1001
  • [8] Critical impact of the kinetics of dendritic cells activation on the in vivo induction of tumor-specific T lymphocytes
    Camporeale, A
    Boni, A
    Iezzi, G
    Degl'Innocenti, E
    Grioni, M
    Mondino, A
    Bellone, M
    CANCER RESEARCH, 2003, 63 (13) : 3688 - 3694
  • [9] Tracking tumor-specific CD8+ T cell responses
    Burke, Kelly P.
    Markson, Samuel C.
    Sharpe, Arlene H.
    TRENDS IN IMMUNOLOGY, 2023, 44 (05) : 326 - 328
  • [10] Delivery of tumor-targeted immunotoxin by tumor-specific T cells
    Swanson, Anna
    Wu, Danli
    Kuiatse, Isere
    Kim, Hong-Sung
    Heslop, Helen
    Brenner, Malcolm
    Yotnda, Patricia
    JOURNAL OF IMMUNOLOGY, 2011, 186