In vivo tracking of tumor-specific T cells

被引：53
作者：
Yee, C
Riddell, SR
Greenberg, PD
机构：
[1] Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA
[2] Univ Washington, Med Ctr, Seattle, WA 98195 USA
来源：
CURRENT OPINION IN IMMUNOLOGY | 2001年 / 13卷 / 02期
关键词：
D O I：
10.1016/S0952-7915(00)00196-5
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Novel immunologic assays now enable visualization of the antigen-specific response to an extent not previously possible. Assessment of not only the numeric frequency but also the functional properties of individual tumor-specific T cells in the endogenous and manipulated immune response has provided insights that will facilitate the development of immunotherapeutic strategies.
引用
收藏
页码：141 / 146
页数：6
相关论文
共 49 条
  • [1] Altman JD, 1998, SCIENCE, V280, P1821
  • [2] Expression of herpes simplex virus ICP47 and human cytomegalovirus US11 prevents recognition of transgene products by CD8+ cytotoxic T lymphocytes
    Berger, C
    Xuereb, S
    Johnson, DC
    Watanabe, KS
    Kiem, HP
    Greenberg, PD
    Riddell, SR
    [J]. JOURNAL OF VIROLOGY, 2000, 74 (10) : 4465 - 4473
  • [3] Putative immunodominant human immunodeficiency virus-specific CD8+ T-Cell responses cannot be predicted by major histocompatibility complex class I haplotype
    Betts, MR
    Casazza, JP
    Patterson, BA
    Waldrop, S
    Trigona, W
    Fu, TM
    Kern, F
    Picker, LJ
    Koup, RA
    [J]. JOURNAL OF VIROLOGY, 2000, 74 (19) : 9144 - 9151
  • [4] HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia
    Bonini, C
    Ferrari, G
    Verzeletti, S
    Servida, P
    Zappone, E
    Ruggieri, L
    Ponzoni, M
    Rossini, S
    Mavilio, F
    Traversari, C
    Bordignon, C
    [J]. SCIENCE, 1997, 276 (5319) : 1719 - 1724
  • [5] RETRACTED: HIV-specific cytotoxic T lymphocytes traffic to lymph nodes and localize at sites of HIV replication and cell death (Retracted article. See vol. 120, pg. 3401, 2010)
    Brodie, SJ
    Patterson, BK
    Lewinsohn, DA
    Diem, K
    Spach, D
    Greenberg, PD
    Riddell, SR
    Corey, L
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2000, 105 (10) : 1407 - 1417
  • [6] In vivo migration and function of transferred HIV-1-specific cytotoxic T cells
    Brodie, SJ
    Lewinsohn, DA
    Patterson, BK
    Jiyamapa, D
    Krieger, J
    Corey, L
    Greenberg, PD
    Riddell, SR
    [J]. NATURE MEDICINE, 1999, 5 (01) : 34 - 41
  • [7] Massive expansion of antigen-specific CD8+ T cells during an acute virus infection
    Butz, EA
    Bevan, MJ
    [J]. IMMUNITY, 1998, 8 (02) : 167 - 175
  • [8] CD8+ T-cell selection, function, and death in the primary immune response in vivo
    Callan, MFC
    Fazou, C
    Yang, HB
    Rostron, T
    Poon, K
    Hatton, C
    McMichael, AJ
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2000, 106 (10) : 1251 - 1261
  • [9] Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus in vivo
    Callan, MFC
    Tan, L
    Annels, N
    Ogg, GS
    Wilson, JDK
    O'Callaghan, CA
    Steven, N
    McMichael, AJ
    Rickinson, AB
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1998, 187 (09) : 1395 - 1402
  • [10] Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes
    Crawford, F
    Kozono, H
    White, J
    Marrack, P
    Kappler, J
    [J]. IMMUNITY, 1998, 8 (06) : 675 - 682
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