The effect of zinc supplementation on antioxidant and lipid peroxidation status during Brachiaria decumbens intoxication in sheep

被引：0
|
作者：
Zhang, SSZ [1 ]
Noordin, MM
Rahman, SOA
Haron, J
机构：
[1] Univ Pertanian Malaysia, Fac Vet Med, Serdang 43400, Selangor, Malaysia
[2] Univ Pertanian Malaysia, Fac Sci & Environm Studies, Dept Chem, Serdang 43400, Selangor, Malaysia
来源：
VETERINARY AND HUMAN TOXICOLOGY | 2001年 / 43卷 / 02期
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D O I：
暂无
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
An attempt was made to clarify the association between zinc (Zn) and antioxidants due to Zn supplementation on lipid peroxidation occurring during Brachiaria decumbens intoxication. The concentration of Zn, copper, malondialdehyde (MDA), superoxide dismutase (SOD), and gluthathione peroxidase (GSH-Px) were determined in tissues. There was a gradual increment in the concentration of Zn and MDA in serum and hepatocytic SOD in groups given Zn + B decumbens. A decline in erythrocytic GSH-Px and SOD, and lower concentration of reduced glutathione in hepatocyte cytosols were also detected in these sheep. It is highly suggestive that Zn supplementation may depress antioxidant status and enhance lipid peroxidation during B decumbens intoxication.
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页码：83 / 87
页数：5
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