Evidence-based approach to thrombophilia testing

被引：42

作者：

Middeldorp, Saskia ^{[1
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Vasc Med, NL-1105 AZ Amsterdam, Netherlands

来源：

JOURNAL OF THROMBOSIS AND THROMBOLYSIS | 2011年 / 31卷 / 03期

关键词：

Thrombophilia; Venous thrombosis; Pulmonary embolism; FACTOR-V-LEIDEN; RECURRENT VENOUS THROMBOEMBOLISM; MOLECULAR-WEIGHT HEPARIN; ACTIVATED PROTEIN-C; LOW-DOSE ASPIRIN; INHERITED THROMBOPHILIA; ASYMPTOMATIC CARRIERS; FAMILY-MEMBERS; PREGNANCY COMPLICATIONS; ANTITHROMBOTIC THERAPY;

D O I：

10.1007/s11239-011-0572-y

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Thrombophilia can be identified in about half of all patients presenting with VTE. Testing has increased tremendously for various indications, but whether the results of such tests help in the clinical management of patients has not been settled. I use evidence from observational studies to conclude that testing for hereditary thrombophilia generally does not alter the clinical management of patients with VTE, with occasional exceptions for women at fertile age. Because testing for thrombophilia only serves limited purpose this should not be performed on a routine basis.

引用

页码：275 / 281

页数：7

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