Vγ2Vδ2+ T cells and anti-microbial immune responses

被引:55
作者
Chen, ZW
Letvin, NL
机构
[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, TB Res Unit, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Viral Pathogenesis, Boston, MA 02115 USA
关键词
gamma delta T cells; TCR; memory responses; immunity; infections; primates;
D O I
10.1016/S1286-4579(03)00074-1
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Vgamma2Vdelta2(+) T cells exist only in primates and constitute the majority of circulating human gammadelta T cells. Recent studies have demonstrated that this unique gammadelta T cell subpopulation can be a component of adaptive immune responses and contribute to anti-microbial immunity to infections. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码:491 / 498
页数:8
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