Zinc-Catalyzed Domino Hydroamination-Alkyne Addition

被引：32
|
作者：
Biyikal, Mustafa [2 ]
Porta, Marta [2 ]
Roesky, Peter W. [1 ]
Blechert, Siegfried [2 ]
机构：
[1] KIT, Inst Anorgan Chem, D-76128 Karlsruhe, Germany
[2] Tech Univ Berlin, Inst Chem, D-10623 Berlin, Germany
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2010年 / 352卷 / 11-12期
关键词：
alkynes; domino reaction; hydroamination; metathesis; propargylamines; zinc; GAMMA; DELTA-ALKYNYL-BETA-AMINO ACID-DERIVATIVES; ANTI-MARKOVNIKOV HYDROAMINATION; RING-CLOSING METATHESIS; H BOND ACTIVATION; TERMINAL ALKYNES; INTRAMOLECULAR HYDROAMINATION; INTERMOLECULAR HYDROAMINATION; EFFICIENT SYNTHESIS; CASCADE REACTIONS; INCREASED REACTIVITY;
D O I：
10.1002/adsc.201000211
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The first zinc-catalyzed one-step synthesis of quaternary propargylamines with four different substituents is described. The domino hydroamination alkyne addition reaction gives access to functionalized propargylamines under mild conditions
引用
收藏
页码：1870 / 1875
页数：6
相关论文
共 50 条
  • [21] Zinc-Catalyzed Alkyne Oxidation/CH Functionalization: Highly Site-Selective Synthesis of Versatile Isoquinolones and -Carbolines
    Li, Long
    Zhou, Bo
    Wang, Yong-Heng
    Shu, Chao
    Pan, Yi-Fei
    Lu, Xin
    Ye, Long-Wu
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 54 (28) : 8245 - 8249
  • [22] Recent developments in enantioselective zinc-catalyzed transformations
    Pellissier, Helene
    COORDINATION CHEMISTRY REVIEWS, 2021, 439
  • [23] Zinc-Catalyzed Phosphonylation of Alcohols with Alkyl Phosphites
    Saito, Yuki
    Cho, Soo Min
    Danieli, Luca Alessandro
    Kobayashi, Shu
    ORGANIC LETTERS, 2020, 22 (08) : 3171 - 3175
  • [24] Zinc-Catalyzed Hydroalkoxylation/Cyclization of Alkynyl Alcohols
    de la Cruz-Martinez, Felipe
    de Sarasa Buchaca, Marc Martinez
    Fernandez-Baeza, Juan
    Sanchez-Barba, Luis F.
    Rodriguez, Ana M.
    Castro-Osma, Jose A.
    Lara-Sanchez, Agustin
    INORGANIC CHEMISTRY, 2021, 60 (07) : 5322 - 5332
  • [25] Zinc-catalyzed alcoholysis of β-lactones and activated β-lactams
    Gross, F.
    Brombacher, H.
    Vahrenkamp, H.
    ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 2007, 633 (5-6): : 865 - 868
  • [26] Zinc-catalyzed oxidative esterification of aromatic aldehydes
    Wu, Xiao-Feng
    TETRAHEDRON LETTERS, 2012, 53 (26) : 3397 - 3399
  • [27] Zinc-Catalyzed Amide Cleavage and Esterification of β-Hydroxyethylamides
    Kita, Yusuke
    Nishii, Yuji
    Higuchi, Takafumi
    Mashima, Kazushi
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 51 (23) : 5723 - 5726
  • [28] Zinc-catalyzed conversion of methanol to hydrocarbons.
    Mehrkhodavandi, P
    Diaconescu, PL
    Bercaw, JE
    Labinger, JA
    Grubbs, RH
    Sunley, GJ
    Kay, R
    Morris, G
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2004, 227 : U1445 - U1445
  • [29] Zinc-Catalyzed Chemoselective Reduction of Esters to Alcohols
    Das, Shoubhik
    Moeller, Konstanze
    Junge, Kathrin
    Beller, Matthias
    CHEMISTRY-A EUROPEAN JOURNAL, 2011, 17 (27) : 7414 - 7417
  • [30] Diastereoselective, Zinc-Catalyzed Alkynylation of α-Bromo Oxocarbenium Ions
    Haidzinskaya, Tatsiana
    Kerchner, Hilary A.
    Liu, Jixin
    Watson, Mary P.
    ORGANIC LETTERS, 2015, 17 (15) : 3857 - 3859
12345