Two-dimensional photonic crystals for sensitive microscale chemical and biochemical sensing

被引:95
作者
Baker, James E. [1 ]
Sriram, Rashmi [2 ]
Miller, Benjamin L. [2 ,3 ,4 ]
机构
[1] Univ Rochester, Dept Phys & Astron, Rochester, NY 14627 USA
[2] Univ Rochester, Dept Biomed Engn, Rochester, NY 14627 USA
[3] Univ Rochester, Dept Dermatol, Rochester, NY 14627 USA
[4] Univ Rochester, Dept Biochem & Biophys, Rochester, NY 14627 USA
关键词
ENHANCED FLUORESCENCE; MICROCAVITY SENSOR; DETECTION LIMIT; WAVE-GUIDES; BIOSENSORS; CHIP; FABRICATION; NANOLASER; CAVITIES; VIRUS;
D O I
10.1039/c4lc01208a
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Photonic crystals - optical devices able to respond to changes in the refractive index of a small volume of space - are an emerging class of label-free chemical-and bio-sensors. This review focuses on one class of photonic crystal, in which light is confined to a patterned planar material layer of sub-wavelength thickness. These devices are small (on the order of tens to hundreds of microns square), suitable for incorporation into lab-on-a-chip systems, and in theory can provide exceptional sensitivity. We introduce the defining characteristics and basic operation of two-dimensional photonic crystal sensors, describe variations of their basic design geometry, and summarize reported detection results from chemical and biological sensing experiments.
引用
收藏
页码:971 / 990
页数:20
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