Malignant versus benign mediastinal lesions: quantitative assessment with diffusion weighted MR imaging

被引：54

作者：

Gumustas, Sevtap ^{[1
]}

Inan, Nagihan ^{[1
]}

Sarisoy, Hasan Tahsin ^{[1
]}

Anik, Yonca ^{[1
]}

Arslan, Arzu ^{[1
]}

Ciftci, Ercument ^{[1
]}

Akansel, Gur ^{[1
]}

Demirci, Ali ^{[1
]}

机构：

[1] Kocaeli Univ, Dept Radiol, Sch Med, Kocaeli Uni Tip Fak Radyol AD, TR-41380 Umuttepe Kocaeli, Turkey

来源：

EUROPEAN RADIOLOGY | 2011年 / 21卷 / 11期

关键词：

Diffusion-weighted MR imaging; Mediastinal lesions; Differentiation; Apparent diffusion coefficients (ADC); Magnetic resonance imaging; LYMPH-NODES; TUMORS; MASSES; CHEST; CT;

D O I：

10.1007/s00330-011-2180-9

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We aimed to evaluate the performance of diffusion-weighted magnetic resonance imaging in differentiating malignant from benign mediastinal lesions. Fifty-three mediastinal lesions were examined with T1- and T2-weighted (W) conventional images. Then, two diffusion-weighted images were obtained with b = 0 and 1000 s/mmA(2) values and apparent diffusion coefficients (ADC) were calculated. The statistical significance of differences between measurements was tested using the Student-t test. The mean ADC of malignant lesions was significantly lower than that of the benign masses (p < 0.001). The cut-off value of a parts per thousand currency signaEuro parts per thousand 1.39 x 10(-3) mmA(2)/s indicated a malignant lesion with a sensitivity of 95% and specificity of 87%. Diffusion-weighted imaging may be helpful in differentiating benign from malignant mediastinal masses.

引用

页码：2255 / 2260

页数：6

共 20 条

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