High Prevalence of Abdominal, Intra-Abdominal and Subcutaneous Adiposity and Clustering of Risk Factors among Urban Asian Indians in North India

被引:70
作者
Bhardwaj, Swati [1 ]
Misra, Anoop [1 ,2 ,3 ]
Misra, Ranjita [4 ]
Goel, Kashish [1 ,5 ]
Bhatt, Surya Prakash [1 ,6 ]
Rastogi, Kavita
Vikram, Naval K. [7 ]
Gulati, Seema [1 ]
机构
[1] Natl Diabet Obes & Cholesterol Dis Fdn N DOC, SDA, New Delhi, India
[2] Fortis Flt Lt Rajan Dhall Hosp, Fortis CDOC Ctr Excellence Diabet Metab Dis & End, New Delhi, India
[3] Fortis Flt Lt Rajan Dhall Hosp, Ctr Internal Med, New Delhi, India
[4] Texas A&M Univ, Dept Hlth & Kinesiol, College Stn, TX USA
[5] Wayne State Univ, Dept Internal Med, Detroit, MI 48202 USA
[6] All India Inst Med Sci, Dept Biochem & Med, New Delhi, India
[7] All India Inst Med Sci, Dept Internal Med, New Delhi, India
关键词
METABOLIC SYNDROME; INSULIN-RESISTANCE; BODY-FAT; TISSUE COMPARTMENTS; OBESITY; POPULATION; DIAGNOSIS; DISEASE;
D O I
10.1371/journal.pone.0024362
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Objective: To assess the prevalence of abdominal obesity including intra-abdominal and subcutaneous adiposity along with other cardiometabolic risk factors in urban Asian Indians living in New Delhi. Methods: We conducted a cross-sectional epidemiological descriptive study with 459 subjects (217 males and 242 females), representing all socio-economic strata in New Delhi. The anthropometric profile [body mass index (BMI), waist circumference (WC) and skinfold thickness], fasting blood glucose (FBG) and lipid profile were recorded. Percent body fat (%BF), total abdominal fat (TAF), intra-abdominal adipose tissue (IAAT) and subcutaneous abdominal adipose tissue (SCAT) were quantified using predictive equations for Asian Indians. Results: The overall prevalence of obesity was high [by BMI (>25 kg/m(2)), 50.1%]. The prevalence of abdominal obesity (as assessed by WC) was 68.9%, while that assessed by TAF was 70.8%. Increased IAAT was significantly higher in females (80.6%) as compared to males (56.7%) (p = 0.00) with overall prevalence being 69.3%. The overall prevalence of high SCAT was 67.8%, more in males (69.1%) vs. females (66.5%, p = 0.5). The prevalence of type 2 diabetes, the metabolic syndrome and hypertension was 8.5%, 45.3% and 29.2%, respectively. Hypertriglyceridemia, hypercholesterolemia and low levels of HDL-c were prevalent in 42.7%, 26.6% and 37% of the subjects, respectively. The prevalence of hypertriglyceridemia was significantly higher in males (p = 0.007); however, low levels of HDL-c were more prevalent in females as compared to males (p = 0.00). Conclusion: High prevalence of generalized obesity, abdominal obesity (by measurement of WC, TAF, IAAT and SCAT) and dysmetabolic state in urban Asian Indians in north India need immediate public health intervention.
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页数:6
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