Green alcoholic solvent and UAE extraction of oleuropein from the Olea europaea L. leaves: Experimental design, optimization, and comparison with Pharmacopoeia method

被引：9
作者：
Vural, Nilufer [1 ]
Cavuldak, Ozge Algan [2 ]
Kenar, Adnan [3 ]
Akay, M. Abdulkadir [3 ]
机构：
[1] Ankara Univ, Fac Engn, Chem Engn Dept, Ankara, Turkey
[2] Zonguldak Bulent Ecevit Univ, Fac Engn, Food Engn Dept, Zonguldak, Turkey
[3] Ankara Univ, Fac Sci, Dept Chem, Ankara, Turkey
来源：
SEPARATION SCIENCE AND TECHNOLOGY | 2020年 / 55卷 / 10期
关键词：
Green alcoholic extraction; UAE; oleuropein; optimization; RSM; ULTRASOUND-ASSISTED EXTRACTION; ANTIOXIDANT ACTIVITY; PHENOLIC-COMPOUNDS; OLIVE LEAVES; LIQUID-EXTRACTION; FLAVONOIDS; MIXTURES; ANTHOCYANINS; TEMPERATURES; SYSTEMS;
D O I：
10.1080/01496395.2019.1606014
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Solvent extraction and UAE were studied for the extraction of the polyphenolic compounds from the olive leaf in MeOH/H2O and EtOH/H2O solvent systems. Box Wilson-CCRD design was used under RSM for the experimental design of alcoholic solvent extraction. Multi-response optimization was solved with the help of pareto areas and optimal input variable values were determined by the desirability function, optimization by fuzzy similar precedable ratio method. It is seen that the developed solvent extraction methods are more advantageous to the European Pharmacopoeia method for especially oleuropein and the other phenolics which have synergetic effect in olive leaf extract.
引用
收藏
页码：1813 / 1828
页数：16
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