Alveolar Macrophage Immunometabolism and Lung Function Impairment in Smoking and Chronic Obstructive Pulmonary Disease

被引：50

作者：

O'Beirne, Sarah L. ^{[1
]}

Kikkers, Sarah Ann ^{[1
]}

Oromendia, Clara ^{[1
]}

Salit, Jacqueline ^{[1
]}

Rostmai, Mahboubeh R. ^{[1
]}

Ballman, Karla V. ^{[1
]}

Kaner, Robert J. ^{[1
]}

Crystal, Ronald G. ^{[1
]}

Cloonan, Suzanne M. ^{[1
]}

机构：

[1] Weill Cornell Med, New York, NY 10065 USA

来源：

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2020年 / 201卷 / 06期

关键词：

INFLAMMATION; DEFICIENT; SMOKERS;

D O I：

10.1164/rccm.201908-1683LE

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

引用

页码：735 / 739

页数：6

共 18 条

[1] Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages [J].

Belchamber, Kylie B. R. ;

Singh, Richa ;

Batista, Craig M. ;

Whyte, Moira K. ;

Dockrell, David H. ;

Kilty, Iain ;

Robinson, Matthew J. ;

Wedzicha, Jadwiga A. ;

Barnes, Peter J. ;

Donnelly, Louise E. .

EUROPEAN RESPIRATORY JOURNAL, 2019, 54 (04)

[2] Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages [J].

Bewley, Martin A. ;

Preston, Julie A. ;

Mohasin, Mohammed ;

Marriott, Helen M. ;

Budd, Richard C. ;

Swales, Julie ;

Collini, Paul ;

Greaves, David R. ;

Craig, Ruth W. ;

Brightling, Christopher E. ;

Donnelly, Louise E. ;

Barnes, Peter J. ;

Singh, Dave ;

Shapiro, Steven D. ;

Whyte, Moira K. B. ;

Dockrell, David H. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 196 (07) :845-855

[3] Severity of airflow limitation is associated with severity of airway inflammation in smokers [J].

Di Stefano, A ;

Capelli, A ;

Lusuardi, M ;

Balbo, P ;

Vecchio, C ;

Maestrelli, P ;

Mapp, CE ;

Fabbri, LM ;

Donner, CF ;

Saetta, M .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1998, 158 (04) :1277-1285

[4] ALVEOLAR INFLAMMATION AND ITS RELATION TO EMPHYSEMA IN SMOKERS [J].

FINKELSTEIN, R ;

FRASER, RS ;

GHEZZO, H ;

COSIO, MG .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1995, 152 (05) :1666-1672

[5] Human alveolar macrophages are deficient in PTEN - The role of endogenous oxidants [J].

Flaherty, DM ;

Monick, MM ;

Hinde, SL .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (08) :5058-5064

[6] Cigarette Smoking Impairs the Bioenergetic Immune Response to Mycobacterium tuberculosis Infection [J].

Gleeson, Laura E. ;

O'Leary, Seonadh M. ;

Ryan, Daniel ;

McLaughlin, Anne Marie ;

Sheedy, Frederick J. ;

Keane, Joseph .

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2018, 59 (05) :572-579

[7] Risk of COPD with obstruction in active smokers with normal spirometry and reduced diffusion capacity [J].

Harvey, Ben-Gary ;

Strulovici-Barel, Yael ;

Kaner, Robert J. ;

Sanders, Abraham ;

Vincent, Thomas L. ;

Mezey, Jason G. ;

Crystal, Ronald G. .

EUROPEAN RESPIRATORY JOURNAL, 2015, 46 (06) :1589-1597

[8] Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking [J].

Heguy, Adriana ;

O'Connor, Timothy P. ;

Luettich, Karsta ;

Worgall, Stefan ;

Cieciuch, Adam ;

Harvey, Ben-Gary ;

Hackett, Neil R. ;

Crystal, Ronald G. .

JOURNAL OF MOLECULAR MEDICINE-JMM, 2006, 84 (04) :318-328

[9] Smoking alters alveolar macrophage recognition and phagocytic ability [J].

Hodge, Sandra ;

Hodge, Greg ;

Ahern, Jessica ;

Jersmann, Hubertus ;

Holmes, Mark ;

Reynolds, Paul N. .

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2007, 37 (06) :748-755

[10] Up-regulation of alveolar macrophage matrix metalloproteinases in HIV1+ smokers with early emphysema [J].

Kaner, Robert J. ;

Santiago, Francisco ;

Crystal, Ronald G. .

JOURNAL OF LEUKOCYTE BIOLOGY, 2009, 86 (04) :912-922

← 1 2 →