Positron emission tomography imaging in oncology

被引:92
作者
Delbeke, D [1 ]
Martin, WH [1 ]
机构
[1] Vanderbilt Univ, Med Ctr, Dept Radiol & Radiol Sci, Nashville, TN 37232 USA
关键词
D O I
10.1016/S0033-8389(05)70319-5
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
This article summarizes the clinical applications of positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) as a radiopharmaceutical for the evaluation of various body tumors. FDG-PET is an imaging modality allowing direct evaluation of cellular glucose metabolism, and most malignant cells have increased levels of glucose transporter proteins and glycolytic enzymes. Therefore, applications for FDG include differentiation of malignant tumors from benign lesions, diagnosis, staging, monitoring therapy, and detecting recurrence of tumors that trap FDG. Currently, the biggest use for FDG imaging is nodes and metastases staging of these tumors.
引用
收藏
页码:883 / +
页数:36
相关论文
共 249 条
[1]   Metastatic head and neck cancer: Role and usefulness of FDG PET in locating occult primary tumors [J].
Aassar, OS ;
Fischbein, NJ ;
Caputo, GR ;
Kaplan, MJ ;
Price, DC ;
Singer, MI ;
Dillon, WP ;
Hawkins, RA .
RADIOLOGY, 1999, 210 (01) :177-181
[2]  
ABRAMS HL, 1950, CANCER, V3, P74, DOI 10.1002/1097-0142(1950)3:1<74::AID-CNCR2820030111>3.0.CO
[3]  
2-7
[4]   Prospective comparison of 18F-FDG PET with conventional imaging modalities (CT, MRI, US) in lymph node staging of head and neck cancer [J].
Adams, S ;
Baum, RP ;
Stuckensen, T ;
Bitter, K ;
Hör, G .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1998, 25 (09) :1255-1260
[5]   Axillary lymph node metastases: Screening with [F-18]2-deoxy-2-fluoro-D-glucose (FDG) PET [J].
Adler, LP ;
Faulhaber, PF ;
Schnur, KC ;
AlKasi, NL ;
Shenk, RR .
RADIOLOGY, 1997, 203 (02) :323-327
[6]   EVALUATION OF BREAST MASSES AND AXILLARY LYMPH-NODES WITH [F-18] 2-DEOXY-2-FLUORO-D-GLUCOSE PET [J].
ADLER, LP ;
CROWE, JP ;
ALKAISI, NK ;
SUNSHINE, JL .
RADIOLOGY, 1993, 187 (03) :743-750
[7]   GRADING LIPOSARCOMAS WITH PET USING [F-18] FDG [J].
ADLER, LP ;
BLAIR, HF ;
WILLIAMS, RP ;
PATHRIA, MN ;
MAKLEY, JT ;
JOYCE, MJ ;
ALKAISI, N ;
MIRALDI, F .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1990, 14 (06) :960-962
[8]   Positron emission tomography in the clinical staging of patients with stage I and II testicular germ cell tumors [J].
Albers, P ;
Bender, H ;
Yilmaz, H ;
Schoeneich, G ;
Biersack, HJ ;
Mueller, SC .
UROLOGY, 1999, 53 (04) :808-811
[9]   Comparative diagnostic accuracy of magnetic resonance imaging and immunoscintigraphy for detection of bone marrow involvement in patients with malignant lymphoma [J].
Altehoefer, C ;
Blum, U ;
Bothmann, J ;
Wustenberg, C ;
Uhrmeister, P ;
Laubenberger, J ;
Lange, W ;
Schwarzkopf, J ;
Moser, E ;
Langer, M .
JOURNAL OF CLINICAL ONCOLOGY, 1997, 15 (05) :1754-1760
[10]  
Alyafei Saleh, 1999, Clin Positron Imaging, V2, P137, DOI 10.1016/S1095-0397(99)00018-7