Systemic therapy of cholangiocarcinoma

被引：0
作者：
Lutz, M. P. [1 ]
Matzdorff, A.
机构：
[1] Caritasklin St Theresia, Med Klin, D-66113 Saarbrucken, Germany
来源：
ONKOLOGE | 2010年 / 16卷 / 09期
关键词：
Cholangiocarcinoma; Palliative therapy; Systemic chemotherapy; Gemcitabine; Cisplatin; BILIARY-TRACT CANCERS; GEMCITABINE;
D O I：
10.1007/s00761-010-1883-x
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The therapy of cholangiocarcinoma is multimodal and includes systemic chemotherapy in addition to local palliative measures depending on the localization and the pattern of spreading. The effectiveness of 5-fluorouracil, gemcitabine and platinum analogues has been confirmed by several non-randomized studies. In a current large randomized phase III study the combination of gemcitabine and cisplatin significantly extended the average survival by 3.6 months compared to gemcitabine.
引用
收藏
页码：898 / 900
页数：3
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