Safety and Efficacy of Ledipasvir/Sofosbuvir in a Genotype 1 HCV Infected Chinese Population: Results from a Phase 3, Clinical Trial

被引：0

作者：

Wei, Lai ^{[1
]}

Xie, Qing ^{[2
]}

Hou, Jinlin ^{[3
]}

Tang, Hong ^{[4
]}

Ning, Qin ^{[5
]}

Cheng, Jun ^{[6
]}

Nan, Yuemin ^{[7
]}

Zhang, Lunli ^{[8
]}

Li, Jun ^{[9
]}

Jiang, Jianning ^{[10
]}

McNabb, Brian L. ^{[11
]}

Zhang, Fangqiu ^{[12
]}

Camus, Gregory ^{[13
]}

Mo, Hongmei ^{[13
]}

McNally, John ^{[11
]}

Brainard, Diana M. ^{[11
]}

Subramanian, Mani ^{[11
]}

Gong, Guozhong ^{[14
]}

Mou, Zhuangbo ^{[15
]}

Wu, Shanming ^{[16
]}

Wang, Qui-Qiang ^{[17
]}

Hu, Peng ^{[18
]}

Gao, Yanhang ^{[19
]}

Jia, Jidong ^{[20
]}

Duan, Zhongping ^{[21
]}

机构：

[1] Peking Univ, Peoples Hosp, Beijing, Peoples R China

[2] Shanghai Jiao Tong Univ, Ruijin Hosp, Shanghai, Peoples R China

[3] Southern Med Univ, Nanfang Hosp, Guangzhou, Guangdong, Peoples R China

[4] Sichuan Univ, West China Hosp, Chengdu, Sichuan, Peoples R China

[5] Huanzhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Wuhan, Hubei, Peoples R China

[6] Capital Med Univ, Beijing Ditan Hosp, Beijing, Peoples R China

[7] Hebei Med Univ, Hosp 3, Shijiazhuang, Hebei, Peoples R China

[8] Nanchang Univ, Affiliated Hosp 1, Nanchang, Jiangxi, Peoples R China

[9] Nanjing Med Univ, Affiliated Hosp 1, Nanjing, Jiangsu, Peoples R China

[10] Guangxi Med Univ, Affiliated Hosp 1, Guangxi, Peoples R China

[11] Gilead Sci Inc, Clin Res, 353 Lakeside Dr, Foster City, CA 94404 USA

[12] Gilead Sci Inc, Biostat, 353 Lakeside Dr, Foster City, CA 94404 USA

[13] Gilead Sci Inc, Virol, 353 Lakeside Dr, Foster City, CA 94404 USA

[14] Cent S Univ, Xiangya Hosp 2, Changsha, Hunan, Peoples R China

[15] Jinan Infect Dis Hosp, Jinan, Shandong, Peoples R China

[16] Clin Ctr Shanghai Publ Hlth, Shanghai, Peoples R China

[17] Peking Univ, Hosp 1, Beijing, Peoples R China

[18] Chongqing Med Univ, Affiliated Hosp 2, Chongqing, Peoples R China

[19] Jilin Univ, Hosp 1, Changchun, Jilin, Peoples R China

[20] Capital Med Univ, Beijing Friendship Hosp, Beijing, Peoples R China

[21] Capital Med Univ, Beijing Youan Hosp, Beijing, Peoples R China

来源：

HEPATOLOGY | 2017年 / 66卷

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

1191

引用

页码：642A / 642A

页数：1

共 50 条

[21] Ledipasvir/sofosbuvir-based treatment of patients with chronic genotype-1 HCV infection and cirrhosis: results from two Phase II studies [J].

Lawitz, Eric ;

Poordad, Fred ;

Hyland, Robert H. ;

Wang, Jing ;

Liu, Lin ;

Dvory-Sobol, Hadas ;

Brainard, Diana M. ;

McHutchison, John G. ;

Gutierrez, Julio A. .

ANTIVIRAL THERAPY, 2016, 21 (08) :679-687

[22] Safety and Efficacy of Ledipasvir/Sofosbuvir for the Treatment of Genotype 1 Hepatitis C in Patients Aged 65 Years or Older: A Retrospective Analysis of Phase 3 [J].

Saab, Sammy ;

Mizokami, Masashi ;

Omata, Masao ;

Mangia, Alessandra ;

Eggleton, Ed ;

Seyedkazemi, Star ;

Zhu, Yanni ;

Knox, Steven J. ;

Pang, Phil ;

Subramanian, G. M. ;

Kowdley, Kris ;

Afdhal, Nezam H. .

GASTROENTEROLOGY, 2015, 148 (04) :S1085-S1085

[23] Safety and Efficacy of Treatment with Once-Daily Ledipasvir/Sofosbuvir (90/400 mg) for 12 Weeks in Genotype 1 HCV-Infected Patients with Severe Renal Impairment [J].

Lawitz, Eric ;

Landis, Charles S. ;

Maliakkal, Benedict J. ;

Bonacini, Maurizio ;

Ortiz-Lasanta, Grisell ;

Zhang, Jie ;

Mogalian, Erik ;

De-Oertel, Shampa ;

Osinusi, Anu O. ;

Brainard, Diana M. ;

McHutchison, John G. ;

Flamm, Steven L. ;

Gordon, Stuart C. ;

Gane, Edward J. .

HEPATOLOGY, 2017, 66 :848A-848A

[24] SAFETY AND EFFICACY OF TREATMENT WITH ONCE-DAILY LEDIPASVIR/SOFOSBUVIR (90/400 MG) FOR 12 WEEKS IN GENOTYPE 1 HCV-INFECTED PATIENTS WITH SEVERE RENAL IMPAIRMENT [J].

Lawitz, Eric ;

Landis, Charles S. ;

Maliakkal, Benedict J. ;

Bonacini, Maurizio ;

Ortiz-Lasanta, Grisell ;

Zhang, Jie ;

Mogalian, Erik ;

De-Oertel, Shampa ;

Osinusi, Anu O. ;

Brainard, Diana M. ;

McHutchison, John G. ;

Yip, Christina Sze Man ;

Huang, Hai Cheng ;

Flamm, Steven L. ;

Gordon, Stuart C. ;

Gane, Edward J. .

GUT, 2018, 67 :A99-A100

[25] Efficacy and safety of ledipasvir/sofosbuvir in 5,028 Mongolian patients infected with genotype 1 hepatitis C virus: A multicenter study [J].

Baatarkhuu, Oidov ;

Lee, Jae Seung ;

Amarsanaa, Jazag ;

Kim, Do Young ;

Ahn, Sang Hoon ;

Naranzul, Nyamsuren ;

Enkhtuya, Damba ;

Choijamts, Nagir ;

Batbayar, Purev ;

Otgonbayar, Radnaa ;

Saruul, Bat-Ulzii ;

Gantuul, Chuluunbaatar ;

Gegeebadrakh, Baljinnyam ;

Tuvshinbayar, Narangerel ;

Badamsuren, Dorjgotov ;

Ulzmaa, Galsan ;

Otgonbold, Jamiyandorj ;

Han, Kwang-Hyub .

CLINICAL AND MOLECULAR HEPATOLOGY, 2021, 27 (01) :125-135

[26] SOFOSBUVIR/LEDIPASVIR WITH AND WITHOUT RIBAVIRIN FOR 8 WEEKS COMPARED TO SOFOSBUVIR/LEDIPASVIR FOR 12 WEEKS IN TREATMENT-NAIVE NON-CIRRHOTIC GENOTYPE-1 HCV-INFECTED PATIENTS: THE PHASE 3 ION-3 STUDY [J].

Kowdley, K. V. ;

Stuart, G. C. ;

Reddy, R. K. ;

Rossaro, L. ;

Bernstein, D. E. ;

An, D. ;

Svarovskaia, E. S. ;

Hyland, R. H. ;

Pang, P. S. ;

Symonds, W. T. ;

Mchutchison, J. G. ;

Muir, A. J. ;

Pockros, P. J. ;

Pound, D. ;

Fried, M. W. .

JOURNAL OF HEPATOLOGY, 2014, 60 (01) :S23-S24

[27] Safety and efficacy of sofosbuvir plus ledipasvir with and without ribavirin for chronic HCV genotype-1 infection: a systematic review and meta-analysis [J].

Ahmed, Hussien ;

Elgebaly, Ahmed ;

Abushouk, Abdelrahman Ibrahim ;

Hammad, Ali Mohamed ;

Attia, Attia ;

Negida, Ahmed .

ANTIVIRAL THERAPY, 2017, 22 (05) :369-379

[28] Sofosbuvir/Ledipasvir With and Without Ribavirin for 8 Weeks Compared to Sofosbuvir/Ledipasvir for 12 Weeks in Treatment-Naive Non-Cirrhotic Genotype-1 HCV-Infected Patients: The Phase 3 Ion-3 Study [J].

Kowdley, Kris V. ;

Gordon, Stuart C. ;

Reddy, K. Rajender ;

Rossaro, Lorenzo ;

Bernstein, David ;

An, Di ;

Svarovskaia, Evguenia ;

Hyland, Rob H. ;

Pang, Phil ;

Symonds, William T. ;

McHutchison, John G. ;

Muir, Andrew J. ;

Pockros, Paul J. ;

Pound, David ;

Fried, Michael W. .

GASTROENTEROLOGY, 2014, 146 (05) :S926-S926

[29] EFFICACY AND SAFETY OF SOFOSBUVIR/VELPATASVIR IN GENOTYPE 3 AND 6 HCV PATIENTS IN EAST CHINA [J].

Wang Donghui ;

Jiang, Suwen ;

Liu, Linsong ;

Fan, Lingyan ;

Hu, Airong .

HEPATOLOGY, 2021, 74 :589A-590A

[30] Safety and Efficacy of Ledipasvir/Sofosbuvir without on-Treatment Laboratory Monitoring in HCV-Infected Rwandans: The Shared 2 Study [J].

Grant, Philip ;

Kabahizi, Jules ;

Mbituyumuremyi, Aimable ;

Van Nuil, Jennifer Ilo ;

Mukabatsinda, Constance ;

Damascene, Makuza Jean ;

Shumbusho, Fabienne ;

Ntirenganya, Cyprien ;

Nsanzimana, Sabin ;

Gupta, Neil .

HEPATOLOGY, 2018, 68 :36A-36A

← 1 2 3 4 5 →