Synthesis of N-Propargylsulfoximines by Copper-Catalyzed A3-Couplings

被引：15

作者：

Cheng, Hanchao ^{[1
]}

Wen, Jian ^{[1
]}

Bolm, Carsten ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, Landoltweg 1, D-52074 Aachen, Germany

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2017年 / 23卷 / 50期

关键词：

aldehyde; alkyne; copper; multicomponent reactions; N-propargylsulfoximine; A(3) REACTIONS; MULTICOMPONENT REACTION; SULFOXIMINES; EFFICIENT; ALDEHYDE; ALKYNES; COMPLEXES; AMINE; PROPARGYLAMINES; DERIVATIVES;

D O I：

10.1002/chem.201700953

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient synthesis of N-propargylsulfoximines was developed through a copper-catalyzed coupling of aldehydes, alkynes, and NH-sulfoximines. The reaction requires no co-catalyst or ligand and shows a wide substrate scope with moderate to good yields.

引用

页码：12100 / 12103

页数：4

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