A case of hypoplastic left heart syndrome and bicuspid aortic valve in monochorionic twins

被引：6

作者：

Mu, TS ^{[1
]}

McAdams, RM ^{[1
]}

Bush, DM ^{[1
]}

机构：

[1] Wilford Hall USAF Med Ctr, MDOS 859th, Lackland AFB, TX 78236 USA

来源：

PEDIATRIC CARDIOLOGY | 2005年 / 26卷 / 06期

关键词：

hypoplastic left heart syndrome; monochorionic twins; genetic factors; environmental influences;

D O I：

10.1007/s00246-005-1016-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The etiology of hypoplastic left heart syndrome (HLHS) remains unclear. Since a genetic cause for HLHS has not been obvious, it is generally considered to be inherited in a multifactorial manner. Studies of twins are valuable in elucidating the genetic contribution to a birth defect such as HLHS. We report a case of monochorionic twins in whom one has HLHS and the other has a bicuspid aortic valve. Predisposing genetic and environmental influences on individuals with identical genotypes, such as twins, may result in discordance of left-sided flow lesions.

引用

页码：884 / 885

页数：2

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