Sprinting without myrostatin: a genetic determinant of athletic prowess

被引：47

作者：

Lee, Se-Jin ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Mol Biol & Genet, Baltimore, MD 21205 USA

来源：

TRENDS IN GENETICS | 2007年 / 23卷 / 10期

关键词：

D O I：

10.1016/j.tig.2007.08.008

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Genetic studies in several species have demonstrated that myostatin (MSTN) normally functions to limit skeletal muscle mass. In a recent study, Mosher et al. reported that a mutation in the canine MSTN gene is responsible for the double-muscling phenotype seen in 'bully' whippets. Furthermore, they show that loss of even one functional MSTN allele seems to confer a competitive advantage to racing whippets, providing the first definitive evidence that loss of myostatin function can enhance athletic performance.

引用

页码：475 / 477

页数：3

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