NUT midline carcinoma as a primary lung tumor: a case report

被引：15
|
作者：
Cao, Jiashun [1 ]
Chen, Donghong [1 ]
Yang, Fan [1 ]
Yao, Jingjing [2 ]
Zhu, Weipeng [1 ]
Zhao, Chuanduo [1 ]
机构：
[1] Tsinghua Univ, Beijing Tsinghua Changgung Hosp, Med Ctr, Dept Thorac Surg, Beijing 102218, Peoples R China
[2] Tsinghua Univ, Beijing Tsinghua Changgung Hosp, Med Ctr, Dept Pathol, Beijing 102218, Peoples R China
来源：
JOURNAL OF THORACIC DISEASE | 2017年 / 9卷 / 12期
关键词：
NUT midline carcinoma; lung tumor; pneumonectomy; BRD-NUT; DIFFERENTIATION; FEATURES; TRACT; TRANSLOCATION; REARRANGEMENT; ONCOPROTEIN; GROWTH;
D O I：
10.21037/jtd.2017.11.50
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
NUT (nuclear protein in testis) midline carcinoma is a rare malignant tumor arising in midline structures, such as head, neck and mediastinum. In the 2015 WHO classification of lung tumours, it was categorized in "Epithelial tumors". However, because of limited clinical data, its biological features have not been fully recognized. We report a case of NUT midline carcinoma presented as a primary lung tumor. Pneumonectomy was performed without any neoadjuvant therapy and it turned out to be a gross total resection. Even so, the prognosis is poor with a disease-free survival of 2 months and an overall survival of 6 months.
引用
收藏
页码：E1045 / E1049
页数：5
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