Achieving Remission as a Routine Goal of Pharmacotherapy in Attention-Deficit Hyperactivity Disorder

被引:28
作者
Antoni Ramos-Quiroga, J. [1 ,2 ]
Casas, Miguel [1 ,2 ]
机构
[1] Univ Autonoma Barcelona, Dept Psychiat, Hosp Univ Vall Hebron, Barcelona 08035, Spain
[2] Univ Autonoma Barcelona, Dept Psychiat & Legal Med, Barcelona 08035, Spain
关键词
IMMEDIATE-RELEASE METHYLPHENIDATE; DAILY ATOMOXETINE TREATMENT; AGE-DEPENDENT DECLINE; PROOF-OF-CONCEPT; DEFICIT/HYPERACTIVITY-DISORDER; OROS METHYLPHENIDATE; RESEARCH CRITERIA; LINKAGE ANALYSIS; DOSE-RESPONSE; DOUBLE-BLIND;
D O I
10.2165/11538450-000000000-00000
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Remission should be the goal of attention-deficit hyperactivity disorder (ADHD) treatment. However, there is no universally accepted definition of remission in ADHD, although clinical studies use a number of criteria. This article examines current research into the concept of remission in ADHD by reviewing the literature for definition and achievement of remission in children and adults with ADHD. Results demonstrate that the concept of remission in ADHD has been proposed by several study groups, using thresholds of validated rating scales to indicate syndromic, symptomatic and functional remission. Several studies have demonstrated the achievement of remission in ADHD children utilizing methylphenidate delivered by an osmotic, controlled-release formulation (OROS (R)) and atomoxetine. However, none has defined a time period over which these criteria must be met for an individual with ADHD to be considered 'in remission'. Standardized remission criteria in ADHD will provide a tool for assessing the effectiveness of treatments for ADHD, and raise treatment standards.
引用
收藏
页码:17 / 36
页数:20
相关论文
共 100 条
[1]   Sex differences in dopamine receptors and their relevance to ADHD [J].
Andersen, SL ;
Teicher, MH .
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2000, 24 (01) :137-141
[2]  
ANDERSON JC, 1987, ARCH GEN PSYCHIAT, V44, P69
[3]   Remission in schizophrenia: Proposed criteria and rationale for consensus [J].
Andreasen, NC ;
Carpenter, WT ;
Kane, JM ;
Lasser, RA ;
Marder, SR ;
Weinberger, DR .
AMERICAN JOURNAL OF PSYCHIATRY, 2005, 162 (03) :441-449
[4]  
[Anonymous], 1985, PSYCHOPHARMACOL BULL, V21, P839
[5]  
[Anonymous], 1987, DIAGNOSTIC STAT MANU, V4th
[6]  
[Anonymous], 2001, MANUAL ASEBA SCHOOL
[7]  
[Anonymous], 2003, Journal of the Korean Neuropsychiatric Association
[8]  
[Anonymous], DIAGN STAT MAN MENT
[9]  
[Anonymous], CAN J CLIN PHARM
[10]  
[Anonymous], 2000, DIAGN STAT MAN MENT, DOI DOI 10.1176/APPI.BOOKS.9780890425787