Flow cytometry assessment of leukocyte functions in vascular pathologies

被引：8

作者：

Freyburger, G ^{[1
]}

Labrouche, S ^{[1
]}

机构：

[1] UNIV BORDEAUX 2,F-33076 BORDEAUX,FRANCE

来源：

HEMATOLOGY AND CELL THERAPY | 1996年 / 38卷 / 06期

关键词：

flow cytometry; polymorphonuclear leukocytes; monocytes; coagulation; vascular diseases;

D O I：

10.1007/s00282-996-0513-y

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Intravascular activation of leukocytes has been shown to be involved in a wide range of different and apparently unrelated clinical situations, such as systemic inflammatory response syndrome, ischemia/reperfusion, disseminated intravascular coagulation, atherosclerosis... All of them involve to different degrees many steps of the inflammation process, with leukocyte accumulation and release of toxic species. Haemostasis, leukocyte functions and their cross-talk are summarized in this paper, as well as the most popular methods used for studying leukocyte functions in vascular pathologies. The strengths and present limitations of now cytometry are analyzed in comparison with the biochemical and functional approaches.

引用

页码：513 / 526

页数：14

共 102 条

[1] HUMAN COAGULATION-FACTOR-V IS ACTIVATED TO THE FUNCTIONAL COFACTOR BY ELASTASE AND CATHEPSIN-G EXPRESSED AT THE MONOCYTE SURFACE [J].