Osteoarthritis: What we have been missing in the patellofemoral joint

被引:16
作者
Clark, Andrea L. [1 ]
机构
[1] Duke Univ, Med Ctr, Orthopaed Res Labs,Div Orthopaed Surg, Dept Surg, Durham, NC 27710 USA
来源
EXERCISE AND SPORT SCIENCES REVIEWS | 2008年 / 36卷 / 01期
关键词
cartilage; chondrocyte; knee; histology; material properties; metabolism;
D O I
10.1097/jes.0b013e31815e4217
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Patellofemoral osteoarthritis is common clinically and often independent of tibiofemoral disease. Intriguingly, the patella demonstrates more severe degeneration earlier in the disease process compared with the juxtaposed femoral groove. Here, we consider three hypotheses influencing this disparity and thus discover crucial insights into the etiology of osteoarthritis.
引用
收藏
页码:30 / 37
页数:8
相关论文
共 30 条
[1]   DIFFERENCES BETWEEN SUB-POPULATIONS OF CULTURED BOVINE ARTICULAR CHONDROCYTES .2. PROTEOGLYCAN METABOLISM [J].
AYDELOTTE, MB ;
GREENHILL, RR ;
KUETTNER, KE .
CONNECTIVE TISSUE RESEARCH, 1988, 18 (03) :223-234
[2]   DIFFERENCES BETWEEN SUB-POPULATIONS OF CULTURED BOVINE ARTICULAR CHONDROCYTES .1. MORPHOLOGY AND CARTILAGE MATRIX PRODUCTION [J].
AYDELOTTE, MB ;
KUETTNER, KE .
CONNECTIVE TISSUE RESEARCH, 1988, 18 (03) :205-222
[3]  
Brandt KD, 2002, BIORHEOLOGY, V39, P221
[4]  
Clark A. L., 2004, Journal of Musculoskeletal Research, V8, P1, DOI 10.1142/S0218957704001223
[5]   Heterogeneity in patellofemoral cartilage adaptation to anterior cruciate ligament transection; chondrocyte shape and deformation with compression [J].
Clark, AL ;
Leonard, TR ;
Barclay, LD ;
Matyas, JR ;
Herzog, W .
OSTEOARTHRITIS AND CARTILAGE, 2006, 14 (02) :120-130
[6]   Opposing cartilages in the patellofemoral joint adapt differently to long-term cruciate deficiency: chondrocyte deformation and reorientation with compression [J].
Clark, AL ;
Leonard, TR ;
Barclay, LD ;
Matyas, JR ;
Herzog, W .
OSTEOARTHRITIS AND CARTILAGE, 2005, 13 (12) :1100-1114
[7]   In situ chondrocyte deformation with physiological compression of the feline patellofemoral joint [J].
Clark, AL ;
Barclay, LD ;
Matyas, JR ;
Herzog, W .
JOURNAL OF BIOMECHANICS, 2003, 36 (04) :553-568
[8]   Contact area and pressure distribution in the feline patellofemoral joint under physiologically meaningful loading conditions [J].
Clark, AL ;
Herzog, W ;
Leonard, TR .
JOURNAL OF BIOMECHANICS, 2002, 35 (01) :53-60
[9]   Molecular basis for differences between human joints [J].
Cole, AA ;
Kuettner, KE .
CELLULAR AND MOLECULAR LIFE SCIENCES, 2002, 59 (01) :19-26
[10]  
EMERY IH, 1973, J ANAT, V116, P103