Pyrrolidinedione based macrocyclic schiff base complexes: synthesis, PXRD, antimicrobial and DNA binding studies

被引：0

作者：

Sangwan, Vikas ^{[1
]}

Singh, D. P. ^{[1
]}

机构：

[1] Natl Inst Technol, Dept Chem, Kurukshetra 136119, Haryana, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY | 2018年 / 57卷 / 10期

关键词：

Template methodology; Macrocycle; DNA binding; Antimicrobial; PXRD; X-RAY; ANTIFERTILITY; NI(II); CU(II);

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A collection of five macrocyclic complexes of Cd(II), Zn(II), Ni(II), Cu(II) and Co(II) have been synthesized through metal ion template [2+2] cyclocondensation of 1,8-diaminonaphthalene and pyrrolidine-2,5-dione. The newly designed metal complexes have been analyzed by various spectroscopic and physico-analytical techniques like UV-visible, elemental analysis, IR, molar conductance, ESI-MS, EPR, H-1-NMR and PXRD. The synthesized macrcocyclic metal complexes have been evaluated for their biocidal effects against some strains of pathogenic microbes. The stoichiometry of the macrocyclic complexes has been confirmed with the assistance of molar conductance, ESI-MS and elemental analysis (CHN). DNA interaction studies have been carried out for the elucidation of type and mode of binding of the complexes with the Herring fish sperm DNA. The geometry optimization has been carried out with the help of molecular mechanics using Chem 3D Ultra Software.

引用

页码：1235 / 1241

页数：7

共 50 条

[41] Synthesis, characterization, antimicrobial, and DNA cleavage studies of metal complexes of coumarin Schiff bases [J].

Phaniband, Mohammedshafi A. ;

Dhumwad, Shreedhar D. ;

Pattan, Shashikanth R. .

MEDICINAL CHEMISTRY RESEARCH, 2011, 20 (04) :493-502

[42] Pentacoordinated diorganotin(IV) complexes of Schiff base ligands: synthesis, characterization, antimicrobial and anticancer studies [J].

Saroya, Sonia ;

Asija, Sonika ;

Deswal, Yogesh ;

Kumar, Naresh ;

Kumar, Deepak ;

Jindal, Deepak Kumar ;

Puri, Prashant ;

Kumar, Sandeep .

RESEARCH ON CHEMICAL INTERMEDIATES, 2022, 48 (11) :4671-4691

[43] Synthesis, characterization, anti-microbial, DNA binding and cleavage studies of Schiff base metal complexes [J].

Jayaseelan, Poomalai ;

Prasad, Selladurai ;

Vedanayaki, Subramanian ;

Rajavel, Rangappan .

ARABIAN JOURNAL OF CHEMISTRY, 2016, 9 :S668-S677

[44] Synthesis, characterization, antioxidant, antimicrobial and DNA binding properties of ruthenium(II), cobalt(II) and nickel(II) complexes of Schiff base containing o-vanillin [J].

Turan, Nevin ;

Buldurun, Kenan ;

Alan, Yusuf ;

Savci, Ahmet ;

Colak, Naki ;

Mantarci, Asim .

RESEARCH ON CHEMICAL INTERMEDIATES, 2019, 45 (06) :3525-3540

[45] Synthesis, spectral characterization, in vitro antimicrobial evaluation and DNA cleavage studies of few macrocyclic complexes [J].

Raman, N. .

JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2009, 86 (11) :1143-1149

[46] Synthesis and characterization of novel Schiff base ligand and their Cu (II) , Zn (II), Co (II), and Ni (II) complexes: DNA binding, antimicrobial activity and docking studies [J].

Saravanaselvam, Sakthi Veni ;

Arulanantham, Xavier ;

Tamilelakkiya, M. ;

Sakthivadivel, R. ;

Ponnusamy, Suguna ;

Pandi, P. ;

Velusamy, P. ;

Muthu, S. Esakki ;

Kumar, K. Ashok .

JOURNAL OF MOLECULAR STRUCTURE, 2025, 1325

[47] Schiff Base Copper(II) and Zinc(II) Complexes: Synthesis, Structures, and Antimicrobial Activities [J].

Zhao, Xiao-Jun ;

Xue, Ling-Wei ;

Zhang, Cai-Xia .

SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY, 2015, 45 (04) :516-520

[48] Explorations on the synthesis, structure, DFT, DNA binding properties and molecular docking of tridentate Schiff base Copper (II) complexes [J].

Lakshmipraba, Jagadeesan ;

Ebenezer, Cheriyan ;

Solomon, Rajadurai Vijay ;

Venkatesan, Muthukumar .

CHEMICAL PHYSICS IMPACT, 2023, 7

[49] Synthesis, Characterization, and DFT Investigation of Innovative Schiff Base Transition Metal Complexes: Molecular Docking and Antimicrobial Activity [J].

Sindhu, Indu ;

Singh, Anshul ;

Deswal, Yogesh ;

Gupta, Neeraj Mohan .

APPLIED ORGANOMETALLIC CHEMISTRY, 2025, 39 (08)

[50] Antimicrobial, photocatalytic action and molecular docking studies of imidazole-based Schiff base complexes [J].

Joseyphus, R. Selwin ;

Reshma, R. ;

Arish, Dasan ;

Elumalai, Viswanathan .

RESULTS IN CHEMISTRY, 2022, 4

← 1 2 3 4 5 →