Enantioselective diethylzinc addition to aldehydes using azetidine-derived chiral catalysts

被引:38
|
作者
Hermsen, PJ [1 ]
Cremers, JGO [1 ]
Thijs, L [1 ]
Zwanenburg, B [1 ]
机构
[1] Catholic Univ Nijmegen, Dept Organ Chem, NSR Inst Mol Struct Design & Synth, NL-6525 ED Nijmegen, Netherlands
关键词
D O I
10.1016/S0040-4039(01)00659-1
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
High levels of enantioselectivity have been achieved in the diethylzinc addition to both aromatic and aliphatic aldehydes, employing readily available N-substituted-azetidinyl(diphenylmethyl)methanols as chiral catalysts. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
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页码:4243 / 4245
页数:3
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