Enantioselective Intramolecular Hydroamination of N-Alkenyl Ureas Catalyzed by tropos BIPHEP-Gold(I) Complexes with Au-Au Interaction

被引：47

作者：

Kojima, Masafumi ^{[1
]}

Mikami, Koichi ^{[1
]}

机构：

[1] Tokyo Inst Technol, Dept Appl Chem, Tokyo 1528550, Japan

来源：

SYNLETT | 2012年 / 23卷 / 01期

关键词：

gold; asymmetric catalysis; hydroamination; alkenes; bimetallic activation; HOMOGENEOUS GOLD CATALYSIS; ASYMMETRIC CATALYSIS; UNACTIVATED ALKENES; CHIRAL ANIONS; ALLENES;

D O I：

10.1055/s-0031-1289875

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Dinuclear gold complexes significantly accelerate intramolecular hydroamination of N-alkenyl ureas via proximal and bimetallic activation of alkene and urea. Tropos BIPHEP-gold complexes having Au-Au interaction affords higher enantioselectivity than the BINAP-gold counterparts without Au-Au interaction.

引用

页码：57 / 61

页数：5

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