Tridax Procumbens Extract Loaded Electrospun PCL Nanofibers: A Novel Wound Dressing Material

被引:16
作者
Suryamathi, Mathiazhagan [1 ]
Ruba, Chidhambaram [1 ]
Viswanathamurthi, Periasamy [1 ]
Balasubramanian, Velramar [2 ]
Perumal, Pachiappan [2 ]
机构
[1] Periyar Univ, Dept Chem, Salem 636011, India
[2] Periyar Univ, Dept Biotechnol, Salem 636011, India
关键词
PCL electrospun nanofibers; Tridax procumbens; immobilization; wound dressing; MEDICINAL-PLANTS; FIBERS;
D O I
10.1007/s13233-019-7022-7
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
To overcome the bacterial infection which may leads to strain the wounds progressively, wound healing medicinal plant was choosen to treat the infection caused by bacteria. Though the medicinal wound healing plants are resistant to bacteria, the bare plant extract may face poor contact with the wound. This necessitate for a carrier for the plant extract. Polycaprolactone (PCL) electrospun nanofibers have been selected as carrier in this work due to its beneficial surface property and biocompatibility. Extract from the medicinal plant Tridax procumbens was immobilized on PCL electrospun nanofibers. The PCL nanofiber and Tridax procumbens extract immobilized nanofibers were characterized by SEM, XRD and EDAX. The morphology, porosity, swelling and weight loss percentage of the electrospun nanofibers have been investigated. The Tridax procumbens-PCL nanofibers were analyzed for its anti-bacterial activity. The results of the work confess that the scaffolds act as an enhancer of wound healing and treating surfaces that contain pathogenic microorganisms especially in hospital environment.
引用
收藏
页码:55 / 60
页数:6
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