Cytogenetic toxicity of Aloe vera (a medicinal plant)

被引：8

作者：

Verma, Anjana ^{[2
]}

Gupta, Ashok K. ^{[2
]}

Kumar, Amod ^{[1
]}

Khan, Parimal K. ^{[1
]}

机构：

[1] Univ Patna, Dept Zool, Patna 800005, Bihar, India

[2] Univ Patna, Dept Bot, Patna 800005, Bihar, India

来源：

DRUG AND CHEMICAL TOXICOLOGY | 2012年 / 35卷 / 01期

关键词：

Herbal drugs; Aloe vera; chromosomal abnormality; mitotic index; GENOTOXICITY; EXTRACT; ASSAYS;

D O I：

10.3109/01480545.2011.567273

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The cytogenetic toxicity of the crude leaf extract of Aloe vera, a medicinal plant, was evaluated in two test systems, onion and Swiss albino mice, using their root tip meristematic and bone marrow cells, respectively. No significant increase in structural abnormalities in chromosomes was observed, but a marked increase in cells with chromosome-number anomalies was found. The extract, however, significantly increased the mitotic index of both cell types.

引用

页码：32 / 35

页数：4

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