Reemergence of gentamicin-susceptible strains of methicillin-resistant Staphylococcus aureus in France:: A phylogenetic approach

被引:24
作者
Blanc, DS [1 ]
Francioli, P
Le Coustumier, A
Gazagne, L
Lecaillon, E
Gueudet, P
Vandenesch, F
Etienne, J
机构
[1] CHU Vaudois, Div Autonome Med Prevent Hosp, CH-1011 Lausanne, Switzerland
[2] Hop Champ le Roi, Neuchatel, Switzerland
[3] CH Marechal Joffre, Perpignan, France
[4] Ctr Natl Reference Toxemies Staphylocoques, Lyon, France
关键词
D O I
10.1128/JCM.39.6.2287-2290.2001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The reemergence of gentamicin-susceptible (Gen(s)) methicillin-resistant Staphylococcus aureus (MRSA) isolates in France between 1992 and 1996 was investigated using a phylogenetic approach (multiprimer randomly amplified polymorphic DNA typing). Eighty-six percent (65 of 85) of the French strains were grouped into one phylogenetic cluster within which all but one Gen(s) strain were grouped into a subcluster. Thus, the reemergence of Gen(s) MRSA strains in France was likely due to the spread of one specific clone which belonged to a cluster comprising most French gentamicin-resistant (Gen(r)) strains. This suggests that the Gen(s) clone has emerged from a Gen(r) strain of this cluster.
引用
收藏
页码:2287 / 2290
页数:4
相关论文
共 13 条
[1]   Reemergence of gentamicin-susceptible strains of methicillin-resistant Staphylococcus aureus: Roles of an infection control program and changes in aminoglycoside use [J].
AubryDamon, H ;
Legrand, P ;
BrunBuisson, C ;
Astier, A ;
Soussy, CJ ;
Leclercq, R .
CLINICAL INFECTIOUS DISEASES, 1997, 25 (03) :647-653
[2]   Unusual spread of a penicillin-susceptible methicillin-resistant Staphylococcus aureus clone in a geographic area of low incidence [J].
Blanc, DS ;
Petignat, C ;
Moreillon, P ;
Entenza, JM ;
Eisenring, MC ;
Kleiber, H ;
Wenger, A ;
Troillet, N ;
Blanc, CH ;
Francioli, P .
CLINICAL INFECTIOUS DISEASES, 1999, 29 (06) :1512-1518
[3]   Methicillin-resistant Staphylococcus aureus:: Phylogenetic relatedness between European epidemic clones and Swiss sporadic strains [J].
Blanc, DS ;
Bañuls, AL ;
Hauser, PM ;
Moreillon, P ;
Francioli, P ;
Tibayrenc, M .
MICROBIAL DRUG RESISTANCE-MECHANISMS EPIDEMIOLOGY AND DISEASE, 2000, 6 (03) :231-238
[4]   MOLECULAR ANALYSIS OF A GENTAMICIN RESISTANCE TRANSPOSON-LIKE ELEMENT ON PLASMIDS ISOLATED FROM NORTH-AMERICAN STAPHYLOCOCCUS-AUREUS STRAINS [J].
BYRNE, ME ;
GILLESPIE, MT ;
SKURRAY, RA .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1990, 34 (11) :2106-2113
[5]  
DELPLANO A, 2000, CLIN MICROBIOL INFEC, V6, P239
[6]  
DERYCK R, 1999, ABSTR CLIN MICR I S3, V5, P117
[7]  
Galdbart JO, 2000, J CLIN MICROBIOL, V38, P185
[8]   CHROMOSOME-MEDIATED AND PLASMID-MEDIATED GENTAMICIN RESISTANCE IN STAPHYLOCOCCUS-AUREUS ENCODED BY TN4001 [J].
GILLESPIE, MT ;
LYON, BR ;
MESSEROTTI, LJ ;
SKURRAY, RA .
JOURNAL OF MEDICAL MICROBIOLOGY, 1987, 24 (02) :139-144
[9]   Fitness and competitive growth advantage of new gentamicin-susceptible MRSA clones spreading in French hospitals [J].
Laurent, F ;
Lelièvre, H ;
Cornu, M ;
Vandenesch, F ;
Carret, G ;
Etienne, J ;
Flandrois, JP .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2001, 47 (03) :277-283
[10]  
Lelièvre H, 1999, J CLIN MICROBIOL, V37, P3452