Diagnostic value of ultrasound and contrast-enhanced ultrasound in septic acute kidney injury

被引：5

作者：

Liu, Pei Qing ^{[1
]}

Ding, Chang Wei ^{[1
]}

Zhang, Ying Chun ^{[1
]}

Ma, Qi ^{[1
]}

Liu, Li Jun ^{[2
]}

机构：

[1] Soochow Univ, Dept Ultrasound, Affiliated Hosp 2, Suzhou, Peoples R China

[2] Soochow Univ, Dept Crit Med, Affiliated Hosp 2, Suzhou, Peoples R China

来源：

JOURNAL OF CLINICAL ULTRASOUND | 2022年 / 50卷 / 04期

关键词：

acute kidney injury; contrast-enhanced ultrasound; Doppler ultrasound; microcirculation; renal perfusion; RENAL BLOOD-FLOW; SEPSIS; FAILURE; ULTRASONOGRAPHY; PERFUSION; SHOCK; MICROCIRCULATION; REDISTRIBUTION; DYSFUNCTION;

D O I：

10.1002/jcu.23118

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

Purpose This study aimed to explore the clinical value of ultrasonic Doppler examination and contrast-enhanced ultrasound (US) in the circulation of septic acute kidney injury (AKI). Methods Patients with intensive care unit-related infection were divided into AKI group and control groups. The AKI group was divided into three subgroups according to the serum creatinine value: stage 1, stage 2, and stage 3. Relevant parameters and blood flow of the renal artery were measured, and further contrast-enhanced US was performed and time-intensity curve was analyzed. Results The renal blood flow (RBF) and time-averaged velocity decreased significantly in the AKI group compared with the control group (p = .021 and p = .001). The peak value decreased and time to peak (TTP) prolonged in the AKI group (p < .001). With the aggravation of the disease, the RBF decreased slightly among subgroups (p = 0.124). However, the peak value gradually decreased and the TTP prolonged (all p < .05). The multiple linear regression model showed that only PI, RI, and TTP were independently and linearly correlated with the serum creatinine value. Conclusions Doppler US and contrast-enhanced US are of great help in the detection of condition changes and prognosis of patients with sepsis-induced AKI.

引用

页码：505 / 514

页数：10

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