Acute fatty liver of pregnancy associated with short-chain acyl-coenzyme A dehydrogenase deficiency

被引：61

作者：

Matern, D

Hart, P

Murtha, AP

Vockley, J

Gregersen, N

Millington, DS

Treem, WR

机构：

[1] Mayo Clin & Mayo Fdn, Dept Lab Med & Pathol, Rochester, MN 55905 USA

[2] Mayo Clin & Mayo Fdn, Dept Med Genet, Rochester, MN 55905 USA

[3] Duke Univ, Med Ctr, Dept Pediat, Durham, NC 27710 USA

[4] Duke Univ, Med Ctr, Dept Obstet, Durham, NC 27710 USA

[5] Univ Aarhus, Res Unit Mol Genet, Aarhus, Denmark

来源：

JOURNAL OF PEDIATRICS | 2001年 / 138卷 / 04期

关键词：

D O I：

10.1067/mpd.2001.111814

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

There is a correlation between pregnancy complications such as acute fatty liver of pregnancy and long-chain 3-hydroxyacl-coenzyme A dehydrogenase (LCHAD) deficiency. We diagnosed another fatty acid beta -oxidation defect, short-chain acyl-coenzyme A dehydrogenase deficiency, in an infant when evaluating him because his mother had acute fatty liver of pregnancy. Other beta -oxidation defects, in addition to LCHAD deficiency, should be considered in children born after pregnancies complicated by liver disease.

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页码：585 / 588

页数：4

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