A colorimetric and fluorescent probe for selective sensing and imaging of hydrogen polysulfides

被引：7

作者：

Huang, Xiaoqin ^{[1
]}

Liu, Hongliang ^{[1
]}

Liu, Gang ^{[1
]}

Wang, Renjie ^{[1
]}

Fan, Congbin ^{[1
]}

Pu, Shouzhi ^{[1
]}

机构：

[1] Jiangxi Sci & Technol Normal Univ, Jiangxi Key Lab Organ Chem, Nanchang 330013, Jiangxi, Peoples R China

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY | 2020年 / 391卷

基金：

中国国家自然科学基金;

关键词：

Hydrogen polysulfides; Naked-eye; Fluorescent probe; 2-fluoro-5-nitrobenzoic acid; Cell imaging; LIVING CELLS; SULFIDE; CONSTRUCTION; PERSULFIDE; MOLECULE; SULFUR;

D O I：

10.1016/j.jphotochem.2020.112373

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A colorimeric and fluorescent probe QLB-CF has been developed for the highly sensitive and specific imaging of hydrogen polysuldes (H2Sn, n > 1). Its selective fluorometric/colorimetric sensing of H2Sn was demonstrated in detail. Upon addition of H2Sn, the probe exhibited fast response to H2Sn along with a remarkable color change from colorless to yellow which could be easily observed by the naked eye. Similarly, the probe exhibited fluorescence response to H2Sn, with approximately 7-fold fluorescence enhancement and the fluorescence color change from none to cyan. In addition, the probe displayed high selectivity towards H2Sn among various analytes. What's more, the probe has been successfully applied to exogenous H2Sn detection and imaging in living cells, allowing us to visualize its sensing potential application in living cells.

引用

页数：7

共 44 条

[1] Hydrogen sulfide augments synaptic neurotransmission in the nucleus of the solitary tract [J].

Austgen, James R. ;

Hermann, Gerlinda E. ;

Dantzler, Heather A. ;

Rogers, Richard C. ;

Kline, David D. .

JOURNAL OF NEUROPHYSIOLOGY, 2011, 106 (04) :1822-1832

[2] Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling [J].

Calvert, John W. ;

Jha, Saurabh ;

Gundewar, Susheel ;

Elrod, John W. ;

Ramachandran, Arun ;

Pattillo, Christopher B. ;

Kevil, Christopher G. ;

Lefer, David J. .

CIRCULATION RESEARCH, 2009, 105 (04) :365-U105

[3] A Single Fluorescent Probe to Visualize Hydrogen Sulfide and Hydrogen Polysulfides with Different Fluorescence Signals [J].

Chen, Wei ;

Pacheco, Armando ;

Takano, Yoko ;

Day, Jacob J. ;

Hanaoka, Kenjiro ;

Xian, Ming .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 55 (34) :9993-9996

[4] A Specific Nucleophilic Ring-Opening Reaction of Aziridines as a Unique Platform for the Construction of Hydrogen Polysulfides Sensors [J].

Chen, Wei ;

Rosser, Ethan W. ;

Zhang, Di ;

Shi, Wen ;

Li, Yilin ;

Dong, Wen-Ji ;

Ma, Huimin ;

Hu, Dehong ;

Xian, Ming .

ORGANIC LETTERS, 2015, 17 (11) :2776-2779

[5] Simultaneous Detection of Glutathione and Hydrogen Polysulfides from Different Emission Channels [J].

Chen, Wenqiang ;

Yue, Xiuxiu ;

Zhang, Hui ;

Li, Wenxiu ;

Zhang, Liangliang ;

Xiao, Qi ;

Huang, Chusheng ;

Sheng, Jiarong ;

Song, Xiangzhi .

ANALYTICAL CHEMISTRY, 2017, 89 (23) :12984-12991

[6] A two-photon ratiometric probe for hydrogen polysulfide (H2Sn): Increase in mitochondrial H2Sn production in a Parkinson's disease model [J].

Choi, Hyeon Jin ;

Lim, Chang Su ;

Cho, Myoung Ki ;

Kang, Ji Su ;

Park, Soo Jin ;

Park, Sang Myun ;

Kim, Hwan Myung .

SENSORS AND ACTUATORS B-CHEMICAL, 2019, 283 :810-819

[7] Development of a novel lysosome-targetable time-gated luminescence probe for ratiometric and luminescence lifetime detection of nitric oxide in vivo [J].

Dai, Zhichao ;

Tian, Lu ;

Song, Bo ;

Liu, Xiangli ;

Yuan, Jingli .

CHEMICAL SCIENCE, 2017, 8 (03) :1969-1976

[8] Small Molecule Signaling Agents: The Integrated Chemistry and Biochemistry of Nitrogen Oxides, Oxides of Carbon, Dioxygen, Hydrogen Sulfide, and Their Derived Species [J].

Fukuto, Jon M. ;

Carrington, Samantha J. ;

Tantillo, Dean J. ;

Harrison, Jason G. ;

Ignarro, Louis J. ;

Freeman, Bruce A. ;

Chen, Andrew ;

Wink, David A. .

CHEMICAL RESEARCH IN TOXICOLOGY, 2012, 25 (04) :769-793

[9] A near-infrared fluorescent probe for the detection of hydrogen polysulfides biosynthetic pathways in living cells and in vivo [J].

Gao, Min ;

Wang, Rui ;

Yu, Fabiao ;

You, Jinmao ;

Chen, Lingxin .

ANALYST, 2015, 140 (11) :3766-3772

[10] Near-Infrared Fluorescent Probe for Imaging Mitochondrial Hydrogen Polysulfides in Living Cells and in Vivo [J].

Gao, Min ;

Yu, Fabiao ;

Chen, Hao ;

Chen, Lingxin .

ANALYTICAL CHEMISTRY, 2015, 87 (07) :3631-3638

← 1 2 3 4 5 →