Novel multicomponent reaction for the combinatorial synthesis of 2-imidazolines

被引：108

作者：

Bon, RS ^{[1
]}

Hong, CG ^{[1
]}

Bouma, MJ ^{[1
]}

Schmitz, RF ^{[1
]}

de Kanter, FJJ ^{[1
]}

Lutz, M ^{[1
]}

Spek, AL ^{[1
]}

Orru, RVA ^{[1
]}

机构：

[1] Free Univ Amsterdam, Dept Chem, NL-1081 HV Amsterdam, Netherlands

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 20期

关键词：

D O I：

10.1021/ol035521g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The three-component condensation between an amine, an aldehyde, and an alpha-acidic isocyanide efficiently provides substituted 2-imidazolines in a one-pot reaction under mild conditions.

引用

页码：3759 / 3762

页数：4

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