The present and future of cerebral tumor surgery in children

被引:8
作者
Black, PM [1 ]
机构
[1] Childrens Hosp, Dept Neurosurg, Boston, MA 02115 USA
关键词
cerebral hemisphere tumors; gene therapy; glioblastomas; astrocytomas; PNET; oligodendrogliomas; image-guided surgery; intraoperative MRI;
D O I
10.1007/PL00013721
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Cerebral hemisphere tumors are less common than posterior fossa tumors in children, but are still important among childhood tumors. At the present time, many are low grade and can be treated satisfactorily with modern surgical techniques. These techniques include image guided surgery in the conventional operating room, brain mapping, and surgery in the intraoperative MRI. Technical sophistication is the chief characteristic of present approaches to cerebral cortical tumors. In the future, surgery for these tumors will require both technical and biological sophistication. Malignant cerebral tumors are invasive and heterogeneous and require new understandings of biology to develop effective treatments. These biological understandings will be added to sophisticated surgical techniques for surgical resection, perhaps with local delivery methods.
引用
收藏
页码:821 / 828
页数:8
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