Alterations in brain connectivity due to plasticity and synaptic delay

被引：14

作者：

Lameu, E. L. ^{[1
]}

Macau, E. E. N. ^{[1
,2
]}

Borges, F. S. ^{[3
]}

Iarosz, K. C. ^{[3
]}

Caldas, I. L. ^{[3
]}

Borges, R. R. ^{[4
]}

Protachevicz, P. R. ^{[5
]}

Viana, R. L. ^{[6
]}

Batista, A. M. ^{[3
,5
,7
]}

机构：

[1] Natl Inst Space Res, Sao Jose Dos Campos, SP, Brazil

[2] Univ Fed Sao Paulo, Sao Jose Dos Campos, Brazil

[3] Univ Sao Paulo, Inst Phys, Sao Jose Dos Campos, Brazil

[4] Fed Technol Univ Parana, Dept Math, Ponta Grossa, Brazil

[5] Univ Estadual Ponta Grossa, Sci Postgrad, Ponta Grossa, Brazil

[6] Univ Fed Parana, Dept Phys, Curitiba, PR, Brazil

[7] Univ Estadual Ponta Grossa, Dept Math & Stat, Ponta Grossa, Brazil

来源：

EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS | 2018年 / 227卷 / 5-6期

基金：

巴西圣保罗研究基金会;

关键词：

TIMING-DEPENDENT PLASTICITY; SYNCHRONIZATION; NETWORKS; NEURONS;

D O I：

10.1140/epjst/e2018-00090-6

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Brain plasticity refers to brain's ability to change neuronal connections, as a result of environmental stimuli, new experiences, or damage. In this work, we study the effects of the synaptic delay on both the coupling strengths and synchronization in a neuronal network with synaptic plasticity. We build a network of Hodgkin-Huxley neurons, where the plasticity is given by the Hebbian rules. We verify that without time delay the synapses become regulated by both the nature (excitatory or inhibitory) and the frequency of the presynaptic and postsynaptic neuron. A presynaptic excitatory (inhibitory) neuron with higher (lower) frequency enhances the synaptic strength if the postsynaptic excitatory (inhibitory) neuron has lower (higher) frequency. When the delay is increased the network presents a non-trivial topology. Regarding the synchronization, only for small values of the synaptic delay this phenomenon is observed.

引用

页码：673 / 682

页数：10

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