The research presented in the paper aims to show how knowledge at work influences the achievement of project benefits in organizations in southern Serbia The subject of this research paper is to examine the elements of knowledge management in a project in southern Serbia. The research aims to ensure the transfer and dissemination of knowledge throughout the organization, to provide the knowledge needed to make the best decisions and business processes, to encourage and ensure the quality development of new knowledge, to support and influence the acquisition of knowledge from other sources and to develop the ability to successfully implementation and use, ensuring that new knowledge is conveyed to employees who need it The purpose is to increase the ability to create the value of an organization through the effective use of knowledge. The task of this type of management is to formulate and implement strategies for developing, acquiring and applying knowledge, improving business processes through knowledge development, monitoring and estimating profits through improved application of knowledge; monitoring and evaluation of management activities in relation to knowledge, its development and application. The paper presents a research and scientific examination of theoretical assumptions and their interconnections, ie the assumption that knowledge management tools positively affect the project benefit; knowledge storage positively affects the project benefit; knowledge transfer positively influences the project benefit The survey was conducted in the field through surveys. 244 questionnaires were filled in 14 organizations. After checking the validity of the questionnaire, the data were statistically processed in the SPSS and LISREL programs.