Roquefortine E, a diketopiperazine from an Australian isolate of Gymnoascus reessii

被引：40
作者：
Clark, B
Capon, RJ [1 ]
Lacey, E
Tennant, S
Gill, JH
机构：
[1] Univ Queensland, Inst Mol Biosci, Ctr Mol Biodivers, St Lucia, Qld 4072, Australia
[2] Microbial Screening Technol Pty Ltd, Smithfield, NSW 2164, Australia
来源：
JOURNAL OF NATURAL PRODUCTS | 2005年 / 68卷 / 11期
关键词：
D O I：
10.1021/np0503101
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The new isoprenylated diketopiperazine roquefortine E (6) has been isolated from an Australian soil isolate of the ascomycete Gymnoascus reessii. The known fungal metabolite roquefortine C (1) was also recovered as the major antibacterial principle, and all structures were assigned by detailed spectroscopic analysis.
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页码：1661 / 1664
页数：4
相关论文
共 30 条
  • [1] Molecular requirements for inhibition of cytochrome P450 activities by roquefortine
    Aninat, C
    Hayashi, Y
    André, F
    Delaforge, M
    [J]. CHEMICAL RESEARCH IN TOXICOLOGY, 2001, 14 (09) : 1259 - 1265
  • [2] ACUTE TOXICITY STUDIES ON ROQUEFORTINE AND PR TOXIN, METABOLITES OF PENICILLIUM-ROQUEFORTI, IN MOUSE
    ARNOLD, DL
    SCOTT, PM
    MCGUIRE, PF
    HARWIG, J
    NERA, EA
    [J]. FOOD AND COSMETICS TOXICOLOGY, 1978, 16 (04): : 369 - 371
  • [3] BIOSYNTHESIS OF THE NEUROTOXIN ALKALOID ROQUEFORTINE
    BARROW, KD
    COLLEY, PW
    TRIBE, DE
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1979, (05) : 225 - 226
  • [4] THE BIOSYNTHESIS OF THE MOLD METABOLITES ROQUEFORTINE AND ASZONALENIN FROM L-[2,4,5,6,7-H-5(2)] TRYPTOPHAN
    BHAT, B
    HARRISON, DM
    LAMONT, HM
    [J]. TETRAHEDRON, 1993, 49 (46) : 10663 - 10668
  • [5] Aspergillicins A-E:: five novel depsipeptides from the marine-derived fungus Aspergillus carneus
    Capon, RJ
    Skene, C
    Stewart, M
    Ford, J
    O'Hair, RAJ
    Williams, L
    Lacey, E
    Gill, JH
    Heiland, K
    Friedel, T
    [J]. ORGANIC & BIOMOLECULAR CHEMISTRY, 2003, 1 (11) : 1856 - 1862
  • [6] Gymnoascolides A-C:: Aromatic butenolides from an Australian isolate of the soil ascomycete Gymnoascus reessii
    Clark, B
    Capon, RJ
    Lacey, E
    Tennant, S
    Gill, JH
    Bulheller, B
    Bringmann, G
    [J]. JOURNAL OF NATURAL PRODUCTS, 2005, 68 (08): : 1226 - 1230
  • [7] Blanchaquinone:: A new anthraquinone from an Australian Streptomyces sp.
    Clark, B
    Capon, RJ
    Stewart, M
    Lacey, E
    Tennant, S
    Gill, JH
    [J]. JOURNAL OF NATURAL PRODUCTS, 2004, 67 (10): : 1729 - 1731
  • [8] Fukumoto K., 2002, US. Patent, Patent No. [US6358957B1, 6358957]
  • [9] Synthesis and biological activities of phenylahistin derivatives
    Kanoh, K
    Kohno, S
    Katada, J
    Takahashi, J
    Uno, I
    Hayashi, Y
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 1999, 7 (07) : 1451 - 1457
  • [10] (-)-Phenylahistin arrests cells in mitosis by inhibiting tubulin polymerization
    Kanoh, K
    Kohno, S
    Katada, J
    Takahashi, J
    Uno, I
    [J]. JOURNAL OF ANTIBIOTICS, 1999, 52 (02) : 134 - 141
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